A-cof
Generic Name
a-cof-10-mg-syrup
Manufacturer
Reputable Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| a cof 10 mg syrup | ৳ 100.00 | N/A |
Description
Overview of the medicine
A-cof 10 mg syrup contains Levocloperastine Fendizoate, a non-opioid antitussive agent used for the symptomatic treatment of non-productive cough. It acts peripherally on the tracheobronchial tree to suppress the cough reflex.
Uses & Indications
Dosage
Adults
10 ml (10 mg Levocloperastine) three times daily. Maximum daily dose 30 ml.
Elderly
No specific dose adjustment generally required, but caution advised due to potential age-related physiological changes.
Renal_impairment
Use with caution; dose adjustment may be necessary in severe renal impairment. Consult a doctor.
How to Take
A-cof 10 mg syrup is for oral administration. It can be taken with or without food. Use the provided measuring spoon or cup for accurate dosing. Shake well before use.
Mechanism of Action
Levocloperastine Fendizoate, the active ingredient in A-cof, acts as a non-opioid antitussive agent. Its primary mechanism involves selectively inhibiting the cough reflex at the peripheral level by acting on the tracheobronchial tree, without affecting the central nervous system or respiratory function at therapeutic doses.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Excreted mainly via urine as metabolites.
Half life
Approximately 5-6 hours.
Absorption
Rapidly absorbed after oral administration, reaching peak plasma concentrations within 1-2 hours.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to Levocloperastine Fendizoate or any component of the formulation.
- Productive cough (where sputum needs to be cleared, as suppressing it can be harmful).
- Severe hepatic impairment.
- Children under 2 years of age.
Drug Interactions
Anticoagulants
No significant interaction reported, but cautious use is advised if co-administered.
Central Nervous System (CNS) Depressants
May potentiate the sedative effects. Concurrent use should be avoided or monitored closely.
Storage
Store in a cool, dry place, below 30°C. Protect from direct sunlight and moisture. Keep out of sight and reach of children.
Overdose
Symptoms of overdose may include drowsiness, nausea, vomiting, and dizziness. In case of an overdose, contact a healthcare professional immediately. Treatment is symptomatic and supportive; gastric lavage may be considered if appropriate.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefits outweigh the risks. Avoid during lactation as Levocloperastine may pass into breast milk and potentially harm the infant. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to Levocloperastine Fendizoate or any component of the formulation.
- Productive cough (where sputum needs to be cleared, as suppressing it can be harmful).
- Severe hepatic impairment.
- Children under 2 years of age.
Drug Interactions
Anticoagulants
No significant interaction reported, but cautious use is advised if co-administered.
Central Nervous System (CNS) Depressants
May potentiate the sedative effects. Concurrent use should be avoided or monitored closely.
Storage
Store in a cool, dry place, below 30°C. Protect from direct sunlight and moisture. Keep out of sight and reach of children.
Overdose
Symptoms of overdose may include drowsiness, nausea, vomiting, and dizziness. In case of an overdose, contact a healthcare professional immediately. Treatment is symptomatic and supportive; gastric lavage may be considered if appropriate.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefits outweigh the risks. Avoid during lactation as Levocloperastine may pass into breast milk and potentially harm the infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture when stored under recommended conditions.
Availability
Pharmacies nationwide
Approval Status
Approved
Patent Status
Generic
Clinical Trials
Clinical trials for Levocloperastine have established its efficacy and safety for treating cough. Ongoing studies may further explore its use in specific patient populations or cough etiologies.
Lab Monitoring
- No specific laboratory monitoring is routinely required for patients taking A-cof 10 mg syrup.
Doctor Notes
- Differentiate between productive and non-productive cough before prescribing; A-cof is indicated for non-productive cough.
- Advise patients against self-medication for persistent cough and to seek medical advice if symptoms do not improve.
- Be cautious in patients with severe hepatic impairment or those taking CNS depressants due to potential additive effects.
Patient Guidelines
- Do not exceed the recommended dose.
- Consult a doctor if your cough persists for more than 7 days or worsens, or if you develop fever, rash, or persistent headache.
- Inform your doctor or pharmacist about all other medications, herbal products, and supplements you are taking.
- Keep out of reach of children.
Missed Dose Advice
If a dose of A-cof 10 mg syrup is missed, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to compensate.
Driving Precautions
A-cof 10 mg syrup may cause drowsiness or dizziness in some individuals. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Stay well-hydrated by drinking plenty of fluids.
- Avoid irritants like smoke, dust, and strong fumes which can aggravate cough.
- Consider using a humidifier in your room to ease throat irritation.
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Global Brand Names
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