Acaril
Generic Name
Ivermectin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| acaril 50 mg tablet | ৳ 15.00 | ৳ 150.00 |
Description
Overview of the medicine
Acaril is an anthelmintic used to treat various parasitic infections.
Uses & Indications
Dosage
Adults
200 mcg/kg orally as a single dose.
Elderly
Use with caution, adjust dose based on renal and hepatic function.
Renal_impairment
No specific dosage adjustment is needed for mild to moderate renal impairment.
How to Take
Take on an empty stomach with water.
Mechanism of Action
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite.
Pharmacokinetics
Onset
Within 2-4 hours.
Excretion
Primarily in feces.
Half life
Approximately 12-36 hours.
Absorption
Rapidly absorbed orally.
Metabolism
Hepatic metabolism.
Side Effects
Contraindications
- Hypersensitivity to ivermectin
- Patients with meningitis
Drug Interactions
Warfarin
May increase INR, monitor closely.
CYP3A4 inhibitors
May increase ivermectin levels.
Storage
Store below 30°C, protect from light and moisture.
Overdose
Treatment is symptomatic and supportive.
Pregnancy & Lactation
Category C. Use only if potential benefit justifies the potential risk to the fetus. Caution should be exercised when ivermectin is administered to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to ivermectin
- Patients with meningitis
Drug Interactions
Warfarin
May increase INR, monitor closely.
CYP3A4 inhibitors
May increase ivermectin levels.
Storage
Store below 30°C, protect from light and moisture.
Overdose
Treatment is symptomatic and supportive.
Pregnancy & Lactation
Category C. Use only if potential benefit justifies the potential risk to the fetus. Caution should be exercised when ivermectin is administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies and drug stores
Approval Status
DGDA Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Ongoing clinical trials may provide further information.
Lab Monitoring
- Liver function tests
- Renal function tests
Doctor Notes
- Monitor for adverse effects
- Educate patients on hygiene
Patient Guidelines
- Take exactly as prescribed
- Report any unusual symptoms
- Complete the full course of treatment
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.
Driving Precautions
May cause dizziness, use caution when driving or operating machinery.
Lifestyle Advice
- Maintain good hygiene
- Avoid close contact with infected individuals
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Acaril Brand
Other medicines available under the same brand name
