Take the tablet whole with a sufficient amount of water, preferably with or after food, to minimize gastrointestinal discomfort. Do not crush or chew.

Aceclofenac primarily acts by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. It shows a preferential inhibition of COX-2 over COX-1, leading to reduced inflammation and pain with potentially fewer gastrointestinal side effects compared to non-selective NSAIDs.

• •Hypersensitivity to Aceclofenac or any component of the tablet
• •Active gastrointestinal bleeding or peptic ulceration
• •Severe heart failure
• •Severe renal or hepatic impairment
• •History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
• •Third trimester of pregnancy

Store in a cool, dry place, away from direct light and moisture. Keep out of reach of children. Do not store above 30°C.

Symptoms of overdose may include headache, nausea, vomiting, epigastric pain, gastrointestinal bleeding, rarely diarrhea, disorientation, excitation, coma, drowsiness, dizziness, tinnitus, fainting or convulsions. In cases of significant poisoning, acute renal failure and liver damage are possible. Treatment is primarily symptomatic and supportive; gastric lavage or activated charcoal may be considered within an hour of ingestion.

Pregnancy Category C (first and second trimesters); avoid in third trimester due to potential premature closure of ductus arteriosus and impaired renal function. Aceclofenac is excreted in breast milk in small amounts, so use with caution in breastfeeding mothers.