Acme's Dextrose 5%
Generic Name
Dextrose 5% Injection
Manufacturer
ACME Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| acmes dextrose 5 injection | ৳ 71.30 | N/A |
Description
Overview of the medicine
Dextrose 5% Injection is a sterile solution of Dextrose (glucose) in Water for Injection, used to supply fluids, electrolytes, and calories. It is primarily used for hydration and as a source of carbohydrate energy.
Uses & Indications
Dosage
Adults
Dosage varies greatly depending on the patient's age, weight, clinical condition, and fluid and caloric requirements. Typically administered by slow intravenous infusion.
Elderly
Similar to adult dosage, but caution should be exercised in patients with pre-existing renal or cardiac conditions to avoid fluid overload.
Renal_impairment
Administer with caution; careful monitoring of fluid and electrolyte balance is necessary to prevent fluid overload or electrolyte disturbances.
How to Take
Administered by slow intravenous infusion, typically into a peripheral or central vein, by or under the direct supervision of a healthcare professional.
Mechanism of Action
Dextrose is a monosaccharide (glucose) that is readily metabolized by the body to produce energy. It increases blood glucose levels, provides calories, and helps to spare body protein. When administered intravenously, it expands plasma volume and maintains extracellular fluid volume.
Pharmacokinetics
Onset
Immediate.
Excretion
Metabolized products (CO2 and water) are excreted. Any excess glucose beyond renal threshold may be excreted in urine.
Half life
Not directly applicable as it is rapidly metabolized; its disappearance from plasma depends on metabolic rate.
Absorption
Administered intravenously, Dextrose is immediately available in the bloodstream.
Metabolism
Metabolized via the glycolytic pathway to carbon dioxide and water, releasing energy.
Side Effects
Contraindications
- Known allergy to corn or corn products (as dextrose is often derived from corn).
- Patients with anuria or severe dehydration without electrolytes.
- Diabetic coma (unless glucose is given to treat hypoglycemia).
- Intracranial or intraspinal hemorrhage where fluid overload might be detrimental.
Drug Interactions
Insulin
Dextrose may counteract the hypoglycemic effect of insulin; careful monitoring is required.
Corticosteroids
May increase blood glucose levels, potentially requiring adjustment of dextrose or insulin dosage.
Storage
Store at controlled room temperature (20-25°C), protect from freezing. Do not use if solution is cloudy, discolored, or contains visible particles.
Overdose
Overdose can lead to hyperglycemia, glycosuria, osmotic diuresis leading to dehydration, and fluid overload (especially in patients with renal or cardiac impairment) resulting in pulmonary edema. Management involves discontinuing the infusion, administering insulin if hyperglycemia is severe, and correcting fluid and electrolyte imbalances.
Pregnancy & Lactation
Dextrose 5% Injection is generally considered safe during pregnancy and lactation. However, careful monitoring of maternal glucose levels is recommended, especially in diabetic or gestational diabetic patients.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years when stored under recommended conditions.
Availability
Hospitals, Clinics, Pharmacies
Approval Status
Approved (Long established)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
As a fundamental and long-established solution, Dextrose 5% injection is not typically the subject of new clinical trials for its primary indications. Its efficacy and safety are well-documented.
Lab Monitoring
- Blood glucose levels
- Serum electrolytes (sodium, potassium, chloride, phosphate, magnesium)
- Fluid balance (input/output, weight changes)
- Renal function (creatinine, BUN)
Doctor Notes
- Monitor blood glucose closely, especially in diabetic patients or those at risk of hyperglycemia.
- Assess fluid and electrolyte status regularly to prevent imbalances. Caution in patients with cardiac or renal insufficiency.
- Ensure proper aseptic technique during administration to prevent infection.
Patient Guidelines
- Dextrose 5% Injection is administered by a healthcare professional in a hospital or clinic setting.
- Inform your doctor or nurse if you experience any pain, swelling, or redness at the injection site.
- Report any unusual symptoms such as excessive thirst, frequent urination, confusion, or difficulty breathing.
Missed Dose Advice
As Dextrose 5% Injection is administered by healthcare professionals in a controlled environment, missed doses are unlikely. Administration should be as per physician's orders.
Driving Precautions
Not applicable, as this medication is administered in a hospital setting and patients requiring it are typically not in a condition to drive.
Lifestyle Advice
- Not directly applicable as this is an acute intravenous therapy. Patients should follow their doctor's advice regarding diet and hydration once oral intake is resumed.
- Maintain a balanced diet and hydration post-treatment as advised by your physician.
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