Take orally with a full glass of water, preferably with or after food to minimize gastrointestinal upset. Do not crush, chew, or break the extended-release tablet.

It works by inhibiting the activity of cyclooxygenase (COX) enzymes, particularly COX-2, which are responsible for the production of prostaglandins. Prostaglandins are mediators of pain, inflammation, and fever. By reducing prostaglandin synthesis, Action-XR alleviates pain and inflammation.

• •Hypersensitivity to the active substance or any excipients
• •Active gastrointestinal bleeding or ulceration
• •Severe renal or hepatic impairment
• •Severe heart failure
• •Third trimester of pregnancy
• •History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Symptoms may include nausea, vomiting, epigastric pain, lethargy, and drowsiness. Management involves symptomatic and supportive care. Gastric lavage, activated charcoal, and forced diuresis may be considered. There is no specific antidote.

Not recommended during the third trimester of pregnancy due to potential fetal harm (premature closure of ductus arteriosus). Use during the first and second trimesters only if clearly needed and the potential benefit outweighs the potential risk. Excreted in breast milk; avoid during lactation or use with caution after consulting a doctor.