Actulose
Generic Name
Lactulose
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| actulose 335 gm oral solution | ৳ 60.22 | N/A |
Description
Overview of the medicine
Actulose is a synthetic sugar used to treat constipation. It is also used to treat hepatic encephalopathy, a complication of liver disease.
Uses & Indications
Dosage
Adults
15-30 ml daily
Elderly
15-30 ml daily
Renal_impairment
No dosage adjustment necessary
How to Take
Can be taken with or without food. Drink plenty of water.
Mechanism of Action
Lactulose is broken down in the colon into acids that draw water into the colon, which helps to soften the stool and make it easier to pass.
Pharmacokinetics
Onset
24-48 hours
Excretion
Feces and urine
Half life
2-3 hours
Absorption
Poorly absorbed from the gastrointestinal tract
Metabolism
Metabolized by colonic bacteria
Side Effects
Contraindications
- Galactosemia
- Intestinal Obstruction
Drug Interactions
Antacids
May decrease the effectiveness of lactulose.
Antibiotics
May reduce the effectiveness of lactulose by decreasing the bacterial flora in the colon.
Storage
Store at room temperature away from heat and moisture.
Overdose
Symptoms of overdose may include diarrhea, abdominal cramps, and electrolyte imbalance. Seek medical attention if overdose is suspected.
Pregnancy & Lactation
Lactulose is considered safe for use during pregnancy and lactation.
Side Effects
Contraindications
- Galactosemia
- Intestinal Obstruction
Drug Interactions
Antacids
May decrease the effectiveness of lactulose.
Antibiotics
May reduce the effectiveness of lactulose by decreasing the bacterial flora in the colon.
Storage
Store at room temperature away from heat and moisture.
Overdose
Symptoms of overdose may include diarrhea, abdominal cramps, and electrolyte imbalance. Seek medical attention if overdose is suspected.
Pregnancy & Lactation
Lactulose is considered safe for use during pregnancy and lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies, drug stores
Approval Status
DGDA Approved
Patent Status
Off-Patent
WHO Essential Medicine
YesClinical Trials
Clinical trials have demonstrated the efficacy of lactulose in treating constipation and hepatic encephalopathy.
Lab Monitoring
- Electrolyte levels
- Ammonia levels (in hepatic encephalopathy)
Doctor Notes
- Consider other causes of constipation before prescribing lactulose.
- Monitor electrolyte levels in patients on long-term therapy.
Patient Guidelines
- Drink plenty of fluids
- Maintain a healthy diet
- Exercise regularly
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time.
Driving Precautions
No specific precautions are necessary.
Lifestyle Advice
- Increase fiber intake
- Avoid straining during bowel movements
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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