Adecut
Generic Name
Montelukast
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| adegut 5 mg suspension | ৳ 28.00 | N/A |
Description
Overview of the medicine
Adecut 5 mg Suspension contains Montelukast, a leukotriene receptor antagonist used for the prevention and long-term treatment of asthma and for the relief of symptoms of seasonal allergic rhinitis in pediatric patients.
Uses & Indications
Dosage
Adults
Generally, Montelukast 5mg suspension is not prescribed for adults; the adult dose is typically 10mg (tablet or granules). Consult physician for specific guidance.
Elderly
No specific dosage adjustment is generally needed for elderly patients taking Montelukast, but 5mg suspension is less common for this age group.
Renal_impairment
No dosage adjustment is necessary for patients with renal impairment. For children 6-14 years: 5 mg (as suspension) once daily in the evening.
How to Take
Administer orally, once daily in the evening. May be taken with or without food. Shake the suspension well before use.
Mechanism of Action
Montelukast selectively antagonizes the CysLT1 receptor, preventing the binding of leukotrienes (LTC4, LTD4, LTE4). Leukotrienes are potent inflammatory mediators involved in asthma and allergic rhinitis, causing bronchoconstriction, mucus secretion, and inflammatory cell recruitment. By blocking these receptors, Montelukast reduces inflammation, improves airflow, and alleviates allergic symptoms.
Pharmacokinetics
Onset
Within 1 day for asthma/allergic rhinitis symptoms.
Excretion
Primarily excreted in feces via bile (approximately 86%), with less than 0.2% excreted in urine.
Half life
Approximately 2.7 to 5.5 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentration achieved in 2-4 hours.
Metabolism
Extensively metabolized in the liver, primarily by CYP3A4, 2C8, and 2C9.
Side Effects
Contraindications
- •Hypersensitivity to Montelukast or any component of the suspension.
- •Acute asthma attacks.
Drug Interactions
Rifampin
May decrease Montelukast levels, clinical monitoring advised.
Phenobarbital
May decrease plasma concentrations of Montelukast.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include abdominal pain, somnolence, thirst, headache, vomiting, and psychomotor hyperactivity. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category B. Use during pregnancy only if clearly needed. Excreted in breast milk; caution advised for nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months from the date of manufacture, specific to manufacturer.
Availability
Available in pharmacies worldwide
Approval Status
Approved worldwide (e.g., FDA, EMA, DGDA)
Patent Status
Off-patent (generic versions available)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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