Alcaft
Generic Name
Alcaftadine 0.25% Ophthalmic Solution
Manufacturer
Various manufacturers (e.g., Allergan, generic companies)
Country
Global (USA, India, Bangladesh, etc.)
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| alcaft 025 eye drop | ৳ 450.00 | N/A |
Description
Overview of the medicine
Alcaftadine 0.25% Ophthalmic Solution is an eye drop used to prevent eye itching associated with allergic conjunctivitis. It belongs to a class of medications called antihistamines.
Uses & Indications
Dosage
Adults
Instill one drop in each eye once daily.
Elderly
No specific dosage adjustment required for elderly patients.
Renal_impairment
No specific dosage adjustment required for renal impairment, as systemic absorption is minimal.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid to create a pouch. Squeeze the drop into the pouch. Do not touch the dropper tip to the eye or any other surface. Close eye gently for a few seconds. If using other eye drops, wait at least 5 minutes between applications.
Mechanism of Action
Alcaftadine is an H1-receptor antagonist and mast cell stabilizer. It works by preventing histamine from binding to H1 receptors in the conjunctiva, thereby blocking the allergic response and reducing symptoms like itching. It also inhibits the release of inflammatory mediators from mast cells.
Pharmacokinetics
Onset
Rapid, within minutes.
Excretion
Primarily excreted unchanged via urine.
Half life
Systemic half-life approximately 1.8 hours (minimal systemic exposure).
Absorption
Systemic absorption is minimal following ocular administration.
Metabolism
Not extensively metabolized. Primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to alcaftadine or any component of the formulation.
Drug Interactions
Other ophthalmic preparations
If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
Storage
Store at 20°C to 25°C (68°F to 77°F). Protect from light. Do not freeze.
Overdose
Overdose is unlikely with topical ophthalmic administration due to minimal systemic absorption. If accidental ingestion occurs, symptomatic and supportive treatment should be initiated.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Caution should be exercised when administered to a nursing mother. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months unopened. Discard 28 days after opening.
Availability
Pharmacies, hospitals, clinics
Approval Status
FDA approved (USA), DGDA approved (Bangladesh)
Patent Status
Generic versions available (Original patent expired)
Clinical Trials
Alcaftadine 0.25% ophthalmic solution has been evaluated in multiple randomized, double-masked, placebo-controlled clinical trials, demonstrating efficacy in reducing ocular itching associated with allergic conjunctivitis.
Lab Monitoring
- No specific laboratory monitoring required.
Doctor Notes
- Advise patients about proper administration technique to avoid contamination.
- Emphasize not to wear contact lenses if eyes are red and to wait before reinserting lenses.
- Monitor for signs of secondary infection if allergic conjunctivitis is severe or persistent.
Patient Guidelines
- Do not wear contact lenses if your eyes are red. Wait 10 minutes after using this medicine before inserting contact lenses.
- Do not touch the tip of the dropper to any surface, including the eye, to avoid contamination.
- Discard the eye drop solution 28 days after opening or as advised by the pharmacist, even if some solution remains.
- Consult your doctor if symptoms worsen or do not improve within 72 hours.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
May cause temporary blurred vision. Do not drive or operate machinery until your vision is clear.
Lifestyle Advice
- Avoid rubbing your eyes, as it can worsen irritation.
- Stay indoors when pollen counts are high during allergy season.
- Use sunglasses outdoors to protect eyes from allergens and irritants.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.