Algerd
Generic Name
Dexlansoprazole
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
algerd 500 mg suspension | ৳ 150.00 | N/A |
Description
Overview of the medicine
Dexlansoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach.
Uses & Indications
Dosage
Adults
30 mg once daily for 4-8 weeks for healing erosive esophagitis; 30 mg once daily for maintenance.
Elderly
No specific dosage adjustment is necessary.
Renal_impairment
No dosage adjustment is necessary for patients with renal impairment.
How to Take
Swallow the capsule whole with water. Can be taken with or without food.
Mechanism of Action
Dexlansoprazole inhibits the H+/K+-ATPase enzyme system at the secretory surface of the gastric parietal cell.
Pharmacokinetics
Onset
Within 1 hour.
Excretion
Excreted in urine and feces.
Half life
1-2 hours.
Absorption
Rapid absorption after oral administration.
Metabolism
Extensively metabolized in the liver by CYP2C19 and CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to dexlansoprazole or any component of the formulation.
- Concomitant use with rilpivirine-containing products.
Drug Interactions
Warfarin
Increased INR and prothrombin time.
Rilpivirine
Decreased rilpivirine concentrations, leading to loss of virologic response.
Storage
Store in a cool, dry place, away from direct sunlight.
Overdose
In case of overdose, seek medical attention immediately. Symptoms may include confusion, drowsiness, blurred vision, tachycardia, nausea, vomiting.
Pregnancy & Lactation
Consult your doctor before use during pregnancy or breastfeeding.
Side Effects
Contraindications
- Hypersensitivity to dexlansoprazole or any component of the formulation.
- Concomitant use with rilpivirine-containing products.
Drug Interactions
Warfarin
Increased INR and prothrombin time.
Rilpivirine
Decreased rilpivirine concentrations, leading to loss of virologic response.
Storage
Store in a cool, dry place, away from direct sunlight.
Overdose
In case of overdose, seek medical attention immediately. Symptoms may include confusion, drowsiness, blurred vision, tachycardia, nausea, vomiting.
Pregnancy & Lactation
Consult your doctor before use during pregnancy or breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies and hospitals
Approval Status
FDA Approved, DGDA Approved
Patent Status
Off-Patent
Clinical Trials
Numerous clinical trials have demonstrated the efficacy and safety of dexlansoprazole for treating erosive esophagitis and GERD.
Lab Monitoring
- Liver function tests
- Vitamin B12 levels (long-term use)
Doctor Notes
- Monitor patients for signs and symptoms of osteoporosis if used long-term.
- Consider periodic vitamin B12 level monitoring.
Patient Guidelines
- Take as directed by your doctor.
- Avoid alcohol and smoking.
- Report any unusual side effects to your doctor.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
Use caution when driving or operating machinery if you experience drowsiness or dizziness.
Lifestyle Advice
- Eat smaller, more frequent meals.
- Avoid foods that trigger heartburn.
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Global Brand Names
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