Medicine Information

Allbeevit

Name: Allbeevit
Brand: Allbeevit
Rating: 4.5 (117 reviews)

Injection50 mg/mLVitamins, B-complexATC: A11EA

Generic Name

B-Complex Vitamins Injection

Manufacturer

Generic Pharma Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
allbeevit 50 mg injection	৳ 8.00	N/A

Description

Overview of the medicine

Allbeevit 50 mg Injection is a parenteral formulation of B-complex vitamins, primarily used for the treatment and prevention of vitamin B deficiencies. It helps maintain overall metabolic health and nerve function.

Uses & Indications

Treatment and prevention of vitamin B deficiencies (e.g., beriberi, pellagra, Wernicke-Korsakoff syndrome).

Nutritional support in conditions associated with poor nutrition, malabsorption (e.g., chronic alcoholism, gastrointestinal disorders, prolonged illness).

Supportive therapy for peripheral neuropathy, neuritis, and other neurological disturbances of vitamin B deficiency origin.

Increased metabolic demand for vitamins (e.g., pregnancy, lactation, strenuous physical activity).

Dosage

Adults

Typically 1 mL (50 mg total B-complex or specific component) administered intramuscularly once daily or as prescribed by a physician, depending on the severity of deficiency and clinical response.

Elderly

No specific dose adjustment is generally required for elderly patients; adult dosage is usually appropriate unless significant renal impairment is present.

Renal_impairment

Generally, no dose adjustment is necessary for water-soluble vitamins in mild to moderate renal impairment. For severe renal impairment, consult a physician, though excess vitamins are typically excreted.

How to Take

Allbeevit 50 mg Injection should be administered by deep intramuscular (IM) injection into a large muscle, such as the gluteal region or thigh. It should not be administered intravenously unless specifically directed by a healthcare professional.

Mechanism of Action

B vitamins act as coenzymes in numerous metabolic processes. Thiamine (B1) is crucial for carbohydrate metabolism, Riboflavin (B2) for energy production, Niacinamide (B3) for cellular respiration, Pyridoxine (B6) for amino acid and neurotransmitter synthesis, and Cyanocobalamin (B12) for DNA synthesis and nerve health. This combination helps restore normal levels of these essential vitamins.

Pharmacokinetics

Onset

Therapeutic effects may begin within minutes to hours, depending on the specific vitamin and deficiency severity.

Excretion

Water-soluble B vitamins and their metabolites are primarily excreted renally via the urine. Excess amounts are readily eliminated.

Half life

Varies by individual B vitamin component: Thiamine (9-18 days), Riboflavin (2-3 hours), Pyridoxine (15-20 days), Niacinamide (20-45 minutes), Cyanocobalamin (6 days to several months, due to storage).

Absorption

Rapidly absorbed into the systemic circulation following intramuscular administration.

Metabolism

Primarily metabolized in the liver, with varying pathways for each B vitamin.

Side Effects

Contraindications

Known hypersensitivity to any component of B-complex vitamins or excipients in the formulation.
Leber's disease or tobacco amblyopia, as Vitamin B12 (if present in the complex) can exacerbate these conditions.

Drug Interactions

Levodopa

Pyridoxine (Vitamin B6) may reverse the antiparkinsonian effects of levodopa (without carbidopa) by increasing its peripheral metabolism.

Phenytoin and Phenobarbital

High doses of pyridoxine (Vitamin B6) may reduce the serum levels and therapeutic effects of phenytoin and phenobarbital.

Isoniazid, Penicillamine, Oral Contraceptives

These medications can increase the requirement for pyridoxine.

Storage

Store in a cool, dry place below 30°C. Protect from light. Do not freeze. Keep out of reach of children.

Overdose

Overdose with water-soluble vitamins is rare due to efficient renal excretion. However, very high, prolonged doses of Pyridoxine (Vitamin B6) can lead to sensory neuropathy, characterized by numbness and tingling in the extremities.

Pregnancy & Lactation

B-complex vitamins are generally considered safe and often beneficial during pregnancy and lactation, as requirements for these vitamins increase. However, use should be under medical supervision, and excessive doses should be avoided.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 x 1 mL ampoules10 x 1 mL ampoules50 x 1 mL ampoules (for institutional use)

Shelf Life

Typically 24 to 36 months from the date of manufacture when stored under recommended conditions.

Availability

Pharmacies, Hospitals

Approval Status

Approved

Patent Status

Generic

WHO Essential Medicine

Yes

Clinical Trials

The efficacy and safety of B-complex vitamins are well-established through extensive historical use and numerous studies. Specific clinical trials for 'Allbeevit 50 mg Injection' as a generic formulation would typically focus on bioequivalence and pharmaceutical quality rather than novel efficacy studies.

Lab Monitoring

Monitoring of serum B vitamin levels may be necessary in cases of suspected deficiency or malabsorption.
Routine monitoring of liver or kidney function is generally not required for standard therapeutic doses, but can be considered in patients with pre-existing conditions.

Doctor Notes

Confirm actual vitamin B deficiency through laboratory tests before initiating long-term parenteral therapy, if clinically indicated.
Educate patients on the potential for yellow discoloration of urine and mild injection site reactions.
Monitor patients on concomitant levodopa therapy for reduced efficacy if high-dose pyridoxine is used.

Patient Guidelines

Follow the exact dosage and administration instructions given by your doctor or healthcare provider.
Report any unusual or severe side effects, especially signs of an allergic reaction, to your doctor immediately.
Do not self-administer the injection unless you have received proper training from a healthcare professional.
Inform your doctor about all other medications, supplements, and herbal products you are taking.

Missed Dose Advice

If a dose of Allbeevit 50 mg Injection is missed, administer it as soon as remembered. If it is almost time for the next scheduled dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up.

Driving Precautions

Allbeevit 50 mg Injection is generally not expected to impair the ability to drive or operate machinery. However, if you experience dizziness or any other side effect that affects concentration, avoid these activities.

Lifestyle Advice

Maintain a balanced and nutritious diet to support overall health and potentially reduce the need for high-dose supplementation.
Avoid excessive alcohol consumption, as it can deplete B vitamin stores in the body.
If you have an underlying condition causing vitamin B deficiency, address that condition with your doctor.