Alleloc
Generic Name
Olopatadine Hydrochloride Ophthalmic Solution 0.1%
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| alleloc 01 eye drop | ৳ 100.00 | N/A |
Description
Overview of the medicine
Alleloc 0.1% Eye Drop is an anti-allergic medication containing Olopatadine Hydrochloride. It is used to relieve eye itching and redness caused by allergic conjunctivitis.
Uses & Indications
Dosage
Adults
Instill 1 drop in the affected eye(s) twice daily, approximately 6 to 8 hours apart.
Elderly
No dosage adjustment is necessary.
Renal_impairment
No dosage adjustment is necessary.
How to Take
For ophthalmic use only. Do not touch the dropper tip to any surface. Remove contact lenses before use and wait at least 10 minutes before reinserting.
Mechanism of Action
Olopatadine is a selective H1-receptor antagonist and a mast cell stabilizer. It inhibits histamine release from mast cells and blocks H1-receptors, thereby preventing and relieving allergic symptoms like itching and redness in the eyes.
Pharmacokinetics
Onset
Within minutes (e.g., 30 minutes).
Excretion
Primarily via urine.
Half life
Approximately 3 hours in plasma, but local ocular effects persist longer.
Absorption
Minimal systemic absorption following ophthalmic administration.
Metabolism
Primarily metabolized by cytochrome P450 enzymes, especially CYP2C8, to two minor metabolites (mono-desmethyl and N-oxide).
Side Effects
Contraindications
- Hypersensitivity to olopatadine hydrochloride or any component of the formulation.
Drug Interactions
Other eye drops
If using other ophthalmic medications, wait at least 5 minutes between applications.
Storage
Store at room temperature (below 30°C), protect from light. Do not freeze.
Overdose
Unlikely with topical ophthalmic administration. Symptomatic and supportive treatment if accidental ingestion occurs.
Pregnancy & Lactation
Use only if the potential benefit justifies the potential risk to the fetus/infant. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to olopatadine hydrochloride or any component of the formulation.
Drug Interactions
Other eye drops
If using other ophthalmic medications, wait at least 5 minutes between applications.
Storage
Store at room temperature (below 30°C), protect from light. Do not freeze.
Overdose
Unlikely with topical ophthalmic administration. Symptomatic and supportive treatment if accidental ingestion occurs.
Pregnancy & Lactation
Use only if the potential benefit justifies the potential risk to the fetus/infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Varies (e.g., 24-36 months for unopened, 4 weeks after opening).
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Patent expired
Clinical Trials
Extensive clinical trials have demonstrated efficacy and safety in allergic conjunctivitis.
Lab Monitoring
- Not typically required for routine use.
Doctor Notes
- Advise patients on proper instillation technique to avoid contamination.
- Reassure patients about minimal systemic absorption and associated side effects.
Patient Guidelines
- Avoid touching the dropper tip to prevent contamination.
- Do not wear contact lenses while experiencing active eye allergy symptoms.
- Discard the bottle 4 weeks after opening.
Missed Dose Advice
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose.
Driving Precautions
May cause temporary blurred vision. If blurred vision occurs, wait until vision clears before driving or operating machinery.
Lifestyle Advice
- Avoid known allergens (e.g., pollen, pet dander) if possible.
- Maintain good eye hygiene.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.