Allertin
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| allertin 125 mg oral solution | ৳ 120.00 | N/A |
Description
Overview of the medicine
Allertin 125 mg Oral Solution is an antihistamine used to relieve symptoms of seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives). It helps alleviate sneezing, runny nose, itchy watery eyes, and skin itching or rashes without causing significant drowsiness.
Uses & Indications
Dosage
Adults
For seasonal allergic rhinitis: 125 mg once daily (as prescribed). For chronic idiopathic urticaria: 125 mg once daily (as prescribed).
Elderly
No specific dose adjustment required for healthy elderly individuals; however, dose adjustments may be necessary for renal impairment.
Renal_impairment
Starting dose 60 mg once daily (for severe impairment, consult physician for specific guidance for 125mg solution).
How to Take
Take orally, with or without food. Use a measuring device to ensure accurate dosing. Do not exceed the prescribed dose.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It binds to histamine H1 receptors, preventing histamine from activating these receptors, thereby inhibiting the symptoms associated with histamine release, such as sneezing, itching, and rhinorrhea.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Mainly excreted unchanged in feces (80%) and urine (11%) via biliary and renal routes.
Half life
Approximately 14.4 hours
Absorption
Rapidly absorbed after oral administration; peak plasma concentrations reached in 1-3 hours.
Metabolism
Minimal hepatic metabolism (less than 5%); primarily via P-glycoprotein.
Side Effects
Contraindications
- Hypersensitivity to Fexofenadine or any excipients in the formulation.
Drug Interactions
Erythromycin and Ketoconazole
May increase fexofenadine plasma concentrations (though generally not clinically significant).
Antacids containing aluminum or magnesium
May decrease fexofenadine absorption. Separate administration by approximately 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, dizziness, and dry mouth. Management involves symptomatic and supportive treatment. Gastric lavage and activated charcoal may be considered if recent ingestion.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed. It is not known whether Fexofenadine is excreted in human milk. Exercise caution when administering to a nursing mother.
Side Effects
Contraindications
- Hypersensitivity to Fexofenadine or any excipients in the formulation.
Drug Interactions
Erythromycin and Ketoconazole
May increase fexofenadine plasma concentrations (though generally not clinically significant).
Antacids containing aluminum or magnesium
May decrease fexofenadine absorption. Separate administration by approximately 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, dizziness, and dry mouth. Management involves symptomatic and supportive treatment. Gastric lavage and activated charcoal may be considered if recent ingestion.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed. It is not known whether Fexofenadine is excreted in human milk. Exercise caution when administering to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities (e.g., FDA, DGDA)
Patent Status
Patent expired (generic versions available)
Clinical Trials
Numerous clinical trials have established the efficacy and safety of fexofenadine in treating seasonal allergic rhinitis and chronic idiopathic urticaria, demonstrating its non-sedating profile.
Lab Monitoring
- No routine lab monitoring is generally required.
Doctor Notes
- Advise patients regarding potential interactions with fruit juices.
- Emphasize correct measurement for oral solution, especially in children.
- Reassure patients about its non-sedating profile compared to older antihistamines.
Patient Guidelines
- Follow your doctor's instructions carefully.
- Use the provided measuring device for accurate dosing.
- Do not take with fruit juices like grapefruit, orange, or apple juice.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Fexofenadine is generally non-drowsy, but individual responses vary. Exercise caution when driving or operating machinery until you know how this medication affects you.
Lifestyle Advice
- Avoid known allergens that trigger your symptoms.
- Maintain a healthy lifestyle to support your immune system.
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Global Brand Names
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