Ambolin
Generic Name
Ambroxol Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ambolin 6 mg pediatric drop | ৳ 25.00 | N/A |
Description
Overview of the medicine
Ambolin 6 mg Pediatric Drop is an oral solution containing Ambroxol Hydrochloride, primarily used as a mucolytic and expectorant to help clear mucus and relieve productive cough in children. It works by making phlegm less viscous and easier to expel.
Uses & Indications
Dosage
Adults
Not typically used for adults in pediatric drop form; adult formulations (e.g., syrup, tablet) are available. For children, refer to pediatric dosage.
Elderly
Not typically used for elderly in pediatric drop form; adult formulations are available. For children, refer to pediatric dosage.
Renal_impairment
Dosage may need to be reduced in severe renal impairment. Consult a physician.
How to Take
Administer orally using the calibrated dropper provided. Can be given with or without food. Ensure accurate measurement of the dose.
Mechanism of Action
Ambroxol works as a secretolytic and secretomotor agent. It stimulates serous glands, increasing the secretion of a less viscous mucus. It also activates cilia, enhancing mucociliary clearance. Additionally, it has local anesthetic and antioxidant properties.
Pharmacokinetics
Onset
Within 30 minutes for mucolytic effect.
Excretion
Mainly excreted renally (about 90%) as metabolites, with a small portion excreted unchanged.
Half life
Approximately 7-12 hours (terminal half-life).
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 1-2.5 hours.
Metabolism
Primarily metabolized in the liver to various inactive metabolites, mainly by conjugation.
Side Effects
Contraindications
- Known hypersensitivity to Ambroxol or other components of the formulation.
- Rare hereditary conditions that may be incompatible with an excipient of the product.
Drug Interactions
Cough suppressants
Should not be used concurrently with cough suppressants, as it may lead to a dangerous accumulation of secretions.
Antibiotics (Amoxicillin, Cefuroxime, Erythromycin)
Ambroxol may increase the penetration of these antibiotics into bronchial secretions.
Storage
Store below 30°C, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, diarrhea, and epigastric pain. Management is generally symptomatic and supportive. Gastric lavage may be considered in severe cases.
Pregnancy & Lactation
Use with caution. While human data is limited, animal studies have not shown direct or indirect harmful effects. Consult a doctor before use during pregnancy or lactation.
Side Effects
Contraindications
- Known hypersensitivity to Ambroxol or other components of the formulation.
- Rare hereditary conditions that may be incompatible with an excipient of the product.
Drug Interactions
Cough suppressants
Should not be used concurrently with cough suppressants, as it may lead to a dangerous accumulation of secretions.
Antibiotics (Amoxicillin, Cefuroxime, Erythromycin)
Ambroxol may increase the penetration of these antibiotics into bronchial secretions.
Storage
Store below 30°C, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, diarrhea, and epigastric pain. Management is generally symptomatic and supportive. Gastric lavage may be considered in severe cases.
Pregnancy & Lactation
Use with caution. While human data is limited, animal studies have not shown direct or indirect harmful effects. Consult a doctor before use during pregnancy or lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months when stored as recommended.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by regulatory authorities
Patent Status
Off-patent
Clinical Trials
Extensively studied for its mucolytic efficacy in respiratory conditions. Ongoing research focuses on its anti-inflammatory and antioxidant properties.
Lab Monitoring
- No specific routine lab monitoring is required.
Doctor Notes
- Advise parents on proper dropper usage to ensure accurate dosing for infants and young children.
- Remind that mucolytics are for productive coughs and may not be suitable for dry coughs.
- Counsel on recognizing signs of hypersensitivity reactions.
Patient Guidelines
- Shake the bottle well before each use.
- Use the provided dropper for accurate dosing.
- Do not exceed the recommended dose.
- Consult a doctor if symptoms persist or worsen.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Ambroxol has no or negligible influence on the ability to drive and use machines.
Lifestyle Advice
- Ensure adequate fluid intake to help thin mucus.
- Maintain a humid environment to ease breathing.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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