Amboxol (Generic)
Generic Name
Ambroxol
Manufacturer
Various Manufacturers
Country
Global
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| amboxol 6 mg pediatric drop | ৳ 23.00 | N/A |
Description
Overview of the medicine
Ambroxol is a mucolytic agent used to treat respiratory conditions associated with viscous or thick mucus, making it easier to cough up.
Uses & Indications
Dosage
Adults
Not applicable for pediatric drop form. Refer to adult formulations.
Elderly
Not applicable for pediatric drop form. Refer to adult formulations.
Renal_impairment
Use with caution in severe renal impairment, dosage adjustment may be needed based on physician's advice.
Children_2_5_years
1 mL (6 mg) twice daily.
Infants_up_to_2_years
0.5 mL (3 mg) twice daily.
How to Take
Administer orally, with or without food. Can be mixed with milk, fruit juice, or water. Use the provided dropper for accurate measurement.
Mechanism of Action
Ambroxol acts by stimulating serous gland cells, increasing bronchial secretions, reducing mucus viscosity, and enhancing mucociliary clearance.
Pharmacokinetics
Onset
Within 30 minutes.
Excretion
Mainly renal excretion (approximately 90%).
Half life
Approximately 7-12 hours.
Absorption
Rapid and almost complete absorption from oral administration.
Metabolism
Primarily hepatic, extensive first-pass metabolism.
Side Effects
Contraindications
- Known hypersensitivity to ambroxol or to any of the excipients.
- Patients with rare hereditary conditions that may be incompatible with an excipient (e.g., fructose intolerance if containing sorbitol).
Drug Interactions
Antitussives
Concomitant use with antitussives (cough suppressants) is not recommended as it may lead to a dangerous accumulation of secretions due to the impaired cough reflex.
Antibiotics (e.g., Amoxicillin, Cefuroxime, Erythromycin, Doxycycline)
Ambroxol has been shown to increase the penetration of certain antibiotics into bronchial secretions, potentially enhancing their therapeutic effect.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose are generally mild and may include nausea, vomiting, diarrhea, and dyspepsia. Management is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category C. Use in pregnancy, especially during the first trimester, only if the potential benefit justifies the potential risk to the fetus. Ambroxol is excreted in breast milk; therefore, caution should be exercised when administered to a nursing mother.
Side Effects
Contraindications
- Known hypersensitivity to ambroxol or to any of the excipients.
- Patients with rare hereditary conditions that may be incompatible with an excipient (e.g., fructose intolerance if containing sorbitol).
Drug Interactions
Antitussives
Concomitant use with antitussives (cough suppressants) is not recommended as it may lead to a dangerous accumulation of secretions due to the impaired cough reflex.
Antibiotics (e.g., Amoxicillin, Cefuroxime, Erythromycin, Doxycycline)
Ambroxol has been shown to increase the penetration of certain antibiotics into bronchial secretions, potentially enhancing their therapeutic effect.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose are generally mild and may include nausea, vomiting, diarrhea, and dyspepsia. Management is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category C. Use in pregnancy, especially during the first trimester, only if the potential benefit justifies the potential risk to the fetus. Ambroxol is excreted in breast milk; therefore, caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date. Check individual product packaging for exact expiry.
Availability
Pharmacies, Hospitals
Approval Status
Generally approved and widely used
Patent Status
Generic
Clinical Trials
Ambroxol has been extensively studied in various clinical trials demonstrating its efficacy and safety as a mucolytic agent. Ongoing research explores new therapeutic applications.
Lab Monitoring
- No specific laboratory monitoring is routinely required for ambroxol.
Doctor Notes
- Educate parents/caregivers on proper administration technique, emphasizing the use of the calibrated dropper for accurate dosing in pediatric patients.
- Advise monitoring for any signs of allergic reactions, including skin rashes or difficulty breathing, and to discontinue use if these occur.
- Stress the importance of adequate hydration to enhance mucolytic effect.
Patient Guidelines
- Administer the medicine exactly as prescribed by your doctor.
- Shake the bottle well before each use.
- Use the calibrated dropper provided to measure the dose accurately.
- Do not exceed the recommended dose.
Missed Dose Advice
If a dose is missed, administer it as soon as remembered. However, if it's almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
Driving Precautions
Ambroxol has no known effects on the ability to drive or operate machinery.
Lifestyle Advice
- Maintain adequate hydration by drinking plenty of fluids to help thin mucus.
- Avoid exposure to irritants like smoke and pollutants that can worsen respiratory conditions.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.