Amocal-AT
Generic Name
Amlodipine Besylate & Atenolol
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| amocal at 5 mg tablet | ৳ 6.02 | ৳ 84.28 |
Description
Overview of the medicine
Amocal-AT is a combination of Amlodipine and Atenolol, used to treat hypertension.
Uses & Indications
Dosage
Adults
One tablet daily, or as directed by the physician.
Elderly
Initiate with lower dose; monitor closely.
Renal_impairment
Dosage adjustment may be required based on creatinine clearance.
How to Take
Swallow the tablet whole with water. Do not crush or chew.
Mechanism of Action
Amlodipine blocks calcium channels, relaxing blood vessels. Atenolol blocks beta-adrenergic receptors, slowing heart rate and decreasing blood pressure.
Pharmacokinetics
Onset
Amlodipine: 6-12 hours. Atenolol: 1-2 hours.
Excretion
Amlodipine: Primarily renal excretion. Atenolol: Primarily renal excretion.
Half life
Amlodipine: 30-50 hours. Atenolol: 6-9 hours.
Absorption
Amlodipine: Well absorbed after oral administration. Atenolol: Approximately 50% absorbed.
Metabolism
Amlodipine: Extensively metabolized in the liver. Atenolol: Minimal metabolism.
Side Effects
Contraindications
- Severe hypotension
- Cardiogenic shock
Drug Interactions
Digoxin
May increase digoxin levels.
Verapamil
May increase the risk of bradycardia and hypotension.
Storage
Store below 30°C in a dry place, away from light.
Overdose
Symptoms may include hypotension, bradycardia, and dizziness. Seek immediate medical attention.
Pregnancy & Lactation
Consult a physician before use during pregnancy or lactation. Atenolol may cross the placenta and appear in breast milk.
Side Effects
Contraindications
- Severe hypotension
- Cardiogenic shock
Drug Interactions
Digoxin
May increase digoxin levels.
Verapamil
May increase the risk of bradycardia and hypotension.
Storage
Store below 30°C in a dry place, away from light.
Overdose
Symptoms may include hypotension, bradycardia, and dizziness. Seek immediate medical attention.
Pregnancy & Lactation
Consult a physician before use during pregnancy or lactation. Atenolol may cross the placenta and appear in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies and hospitals
Approval Status
DGDA Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Clinical trials have demonstrated the efficacy of Amlodipine and Atenolol in reducing blood pressure.
Lab Monitoring
- Blood pressure monitoring
- ECG
Doctor Notes
- Monitor potassium levels periodically.
- Assess renal function regularly.
Patient Guidelines
- Take medication at the same time each day.
- Monitor blood pressure regularly.
- Inform your doctor about all medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
May cause dizziness or fatigue. Use caution when driving or operating machinery.
Lifestyle Advice
- Maintain a healthy diet.
- Exercise regularly.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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