Amoxicon
Generic Name
Amoxicillin
Manufacturer
Local Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| amoxicon 125 mg suspension | ৳ 70.00 | N/A |
Description
Overview of the medicine
Amoxicillin is a broad-spectrum penicillin antibiotic used to treat a variety of bacterial infections.
Uses & Indications
Dosage
Adults
Typically 250 mg to 500 mg every 8 hours, or 500 mg to 875 mg every 12 hours, depending on infection severity. For suspensions, 125 mg/5 ml is primarily for pediatric use, so adult dosage would require higher strength preparations.
Elderly
Similar to adults, but dosage adjustment may be needed based on renal function.
Renal_impairment
Dosage adjustment is necessary for patients with impaired renal function (e.g., reduce dose or extend dosing interval).
How to Take
Shake well before use. Can be taken with or without food. Use a measuring spoon or cup for accurate dosing.
Mechanism of Action
Amoxicillin works by inhibiting the synthesis of bacterial cell walls, leading to bacterial lysis and death.
Pharmacokinetics
Onset
Approximately 30-60 minutes.
Excretion
Primarily excreted by the kidneys through both glomerular filtration and tubular secretion.
Half life
About 1 to 1.5 hours in adults with normal renal function.
Absorption
Rapidly and well absorbed from the gastrointestinal tract, especially when taken orally.
Metabolism
Partially metabolized to inactive metabolites; a significant portion is excreted unchanged.
Side Effects
Contraindications
- History of hypersensitivity to penicillin antibiotics
- History of hypersensitivity to cephalosporins (cross-reactivity)
Drug Interactions
Warfarin
May enhance anticoagulant effect, monitor INR.
Allopurinol
Increased risk of skin rash.
Methotrexate
May increase methotrexate toxicity.
Oral Contraceptives
May reduce efficacy of oral contraceptives.
Storage
Store dry powder below 30°C, protected from moisture. Store reconstituted suspension in a refrigerator (2-8°C) and do not freeze.
Overdose
Symptoms may include gastrointestinal distress (nausea, vomiting, diarrhea) and renal impairment (in rare cases). Treatment is symptomatic and supportive; hemodialysis may be used in severe cases.
Pregnancy & Lactation
Generally considered safe during pregnancy (Category B). Small amounts pass into breast milk, generally considered safe but use with caution and monitor infant for diarrhea or rash.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Dry powder: 2-3 years. Reconstituted suspension: 7-14 days when refrigerated.
Availability
Pharmacies, Hospitals
Approval Status
Widely Approved
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Amoxicillin has been extensively studied since its introduction, with numerous clinical trials establishing its efficacy and safety across a wide range of bacterial infections.
Lab Monitoring
- Liver and kidney function tests for prolonged high-dose therapy.
- Complete blood count (CBC) during extended treatment.
Doctor Notes
- Ensure proper diagnosis to rule out viral infections before prescribing.
- Advise patients on the importance of completing the full course.
- Be aware of potential drug interactions, especially with warfarin and oral contraceptives.
Patient Guidelines
- Complete the entire course of medication, even if symptoms improve.
- Do not save medication for future infections or share it with others.
- Contact your doctor if symptoms do not improve or worsen.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
Amoxicillin generally does not affect the ability to drive or operate machinery. However, if you experience dizziness or allergic reactions, avoid such activities.
Lifestyle Advice
- Maintain good hygiene to prevent spread of infection.
- Stay hydrated by drinking plenty of fluids.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.