Ampirex
Generic Name
Ritonavir
Manufacturer
AbbVie Inc.
Country
USA
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ampirex 500 mg injection | ৳ 22.49 | N/A |
Description
Overview of the medicine
Ampirex is a protease inhibitor used to treat HIV-1 infection.
Uses & Indications
Dosage
Adults
100 mg twice daily with other protease inhibitors.
Elderly
Use with caution, monitor renal and hepatic function.
Renal_impairment
No dosage adjustment necessary for mild to moderate renal impairment. Use with caution in severe renal impairment.
How to Take
Take with food to improve absorption.
Mechanism of Action
Ritonavir inhibits the HIV-1 protease enzyme, preventing viral maturation.
Pharmacokinetics
Onset
Within hours
Excretion
Feces and Urine
Half life
3-5 hours
Absorption
Rapidly absorbed, bioavailability affected by food.
Metabolism
Hepatic via CYP3A4
Side Effects
Contraindications
- Hypersensitivity to ritonavir
- Co-administration with drugs highly dependent on CYP3A for clearance, for which elevated plasma concentrations are associated with serious and/or life-threatening events (e.g., ergot derivatives, cisapride, pimozide)
Drug Interactions
Ergot alkaloids
Concomitant use may cause acute ergot toxicity.
CYP3A4 substrates
Ritonavir is a potent CYP3A4 inhibitor and can increase plasma concentrations of many drugs metabolized by this enzyme.
Storage
Store at room temperature (20-25°C). Protect from moisture.
Overdose
Symptoms of overdose may include nausea, vomiting, diarrhea. Seek immediate medical attention.
Pregnancy & Lactation
Consult your doctor before use during pregnancy. Ritonavir can pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies and Hospitals
Approval Status
FDA Approved
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have demonstrated the efficacy of ritonavir in treating HIV-1 infection.
Lab Monitoring
- Liver function tests
- Viral load
Doctor Notes
- Monitor for drug interactions.
- Adjust dosage based on clinical response and tolerability.
Patient Guidelines
- Take as directed by your doctor.
- Do not stop taking this medication without consulting your doctor.
- Store at room temperature away from moisture and heat.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Driving Precautions
Use caution when driving or operating machinery if you experience dizziness or drowsiness.
Lifestyle Advice
- Maintain a healthy diet.
- Practice safe sex.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.