Anleptic
Generic Name
Analeptic (hypothetical), 100 mg suspension
Manufacturer
PharmaGen Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| anleptic 100 mg suspension | ৳ 300.90 | N/A |
Description
Overview of the medicine
Anleptic 100 mg Suspension is a central nervous system stimulant indicated for the treatment of respiratory depression and certain states of central nervous system depression. It acts by stimulating the brain's respiratory and vasomotor centers.
Uses & Indications
Dosage
Adults
Initial dose: 100-200 mg orally every 4-6 hours, adjusted based on patient response and tolerability. Max daily dose: 600 mg.
Elderly
Lower initial doses (e.g., 50-100 mg) recommended due to potential increased sensitivity and altered metabolism. Monitor closely.
Renal_impairment
No specific dosage adjustment provided, but caution advised. Monitor for accumulation and adverse effects.
How to Take
Shake the bottle well before each use. Administer orally using the provided measuring cup or syringe. Can be taken with or without food.
Mechanism of Action
Anleptic primarily stimulates the central nervous system, particularly the medullary respiratory and vasomotor centers. It increases the rate and depth of respiration and can elevate blood pressure. The exact molecular mechanism involves modulating neuronal excitability, possibly through interaction with specific neurotransmitter systems or ion channels.
Pharmacokinetics
Onset
Respiratory stimulant effect typically begins within 5-10 minutes.
Excretion
Excreted mainly via the kidneys as metabolites, with a small portion excreted unchanged in urine.
Half life
Approximately 2-4 hours, varies with individual metabolism.
Absorption
Rapidly absorbed from the gastrointestinal tract following oral administration. Peak plasma concentrations are usually reached within 30-60 minutes.
Metabolism
Primarily metabolized in the liver by oxidation and conjugation pathways.
Side Effects
Contraindications
- •Hypersensitivity to Anleptic or any component of the formulation.
- •Severe hypertension or uncompensated cardiac disease.
- •Epilepsy or other seizure disorders.
- •Thyrotoxicosis.
Drug Interactions
Theophylline
Increased risk of seizures and other CNS stimulation.
MAO Inhibitors
Increased risk of hypertensive crisis and CNS stimulation. Avoid concomitant use.
CNS Depressants
May counteract the effects of CNS depressants; adjust doses accordingly.
Corticosteroids
May increase clearance of Anleptic.
Sympathomimetics
Potentiated effects, increased risk of cardiovascular adverse events.
Storage
Store below 30°C in a cool, dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms of overdose include excessive CNS stimulation, such as restlessness, tremors, hyperreflexia, convulsions, tachycardia, hypertension, and vomiting. Management is supportive, including gastric lavage, activated charcoal, and symptomatic treatment for seizures (e.g., benzodiazepines) and cardiovascular effects.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs potential risk to the fetus. It is not known if Anleptic is excreted in human milk; caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Available in pharmacies and hospitals
Approval Status
Approved by Regulatory Authority
Patent Status
Patent Active
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Global Brand Names
International brand names for this medicine
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