Antikof
Generic Name
antikof-100-mg-syrup
Manufacturer
Reputable Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| antikof 100 mg syrup | ৳ 80.00 | N/A |
Description
Overview of the medicine
Antikof 100 mg Syrup is an antitussive medication used for the symptomatic relief of dry, unproductive cough. It contains Levocloperastine, which works by suppressing the cough reflex.
Uses & Indications
Dosage
Adults
10 ml (70 mg) three times daily or as directed by physician.
Elderly
No specific dose adjustment required, but caution is advised due to potential increased sensitivity.
Renal_impairment
Use with caution; dose adjustment may be necessary in severe renal impairment.
Children_6_12_years
5 ml (35 mg) three times daily.
How to Take
For oral administration. Can be taken with or without food. Use the provided measuring cup for accurate dosing.
Mechanism of Action
Levocloperastine is a non-opioid antitussive agent that acts primarily by centrally inhibiting the cough reflex without affecting the respiratory center. It also possesses some peripheral antitussive activity.
Pharmacokinetics
Onset
30-60 minutes
Excretion
Primarily excreted in urine as metabolites, with a small portion excreted via feces.
Half life
Approximately 4-6 hours
Absorption
Rapidly absorbed after oral administration, reaching peak plasma concentrations within 1-2 hours.
Metabolism
Extensively metabolized in the liver, primarily via glucuronidation and hydroxylation.
Side Effects
Contraindications
- Hypersensitivity to Levocloperastine or any component of the formulation.
- Patients with productive cough where mucolytic agents are indicated.
- Not recommended for children under 6 years of age without medical supervision.
Drug Interactions
MAO Inhibitors
Concomitant use with MAO inhibitors is not recommended due to potential for increased adverse effects.
CNS Depressants
May enhance the sedative effects of CNS depressants (e.g., alcohol, hypnotics, sedatives, antihistamines).
Storage
Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, nausea, vomiting, dizziness, and mild hypotension. Management is symptomatic and supportive, including gastric lavage or activated charcoal if appropriate.
Pregnancy & Lactation
Use in pregnancy and lactation only if clearly needed and the potential benefits outweigh the possible risks. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to Levocloperastine or any component of the formulation.
- Patients with productive cough where mucolytic agents are indicated.
- Not recommended for children under 6 years of age without medical supervision.
Drug Interactions
MAO Inhibitors
Concomitant use with MAO inhibitors is not recommended due to potential for increased adverse effects.
CNS Depressants
May enhance the sedative effects of CNS depressants (e.g., alcohol, hypnotics, sedatives, antihistamines).
Storage
Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, nausea, vomiting, dizziness, and mild hypotension. Management is symptomatic and supportive, including gastric lavage or activated charcoal if appropriate.
Pregnancy & Lactation
Use in pregnancy and lactation only if clearly needed and the potential benefits outweigh the possible risks. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Levocloperastine in the symptomatic treatment of dry cough in adults and children.
Lab Monitoring
- No specific routine laboratory monitoring is typically required.
Doctor Notes
- Advise patients on proper dosage and duration of treatment. Emphasize that this medication is for dry cough.
- Monitor for CNS depressant effects, especially in elderly patients or those concomitantly using other CNS depressants.
- Instruct patients to seek medical advice if cough persists or worsens.
Patient Guidelines
- Do not exceed the recommended dose or duration of treatment.
- Consult a doctor if your cough persists for more than a week, recurs, or is accompanied by fever, rash, or persistent headache.
- Shake the bottle well before each use.
- This medication is intended for dry cough and should not be used for productive coughs unless advised by a doctor.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.
Driving Precautions
Antikof 100 mg Syrup may cause drowsiness or dizziness. Patients should be advised not to drive or operate heavy machinery if they experience these effects.
Lifestyle Advice
- Maintain adequate hydration by drinking plenty of fluids.
- Avoid exposure to irritants such as smoke, dust, and allergens that may worsen cough.
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Global Brand Names
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