Aquafresh
Generic Name
Ciprofloxacin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Description
Overview of the medicine
Ciprofloxacin is a broad-spectrum antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
250-750 mg every 12 hours depending on the severity and type of infection.
Elderly
Dosage adjustment may be necessary due to reduced renal function.
Renal_impairment
Dosage adjustment is required based on creatinine clearance.
How to Take
Administer orally with or without food. Drink plenty of fluids.
Mechanism of Action
Inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination.
Pharmacokinetics
Onset
Within 1-2 hours
Excretion
Primarily excreted in the urine as unchanged drug.
Half life
Approximately 4-5 hours
Absorption
Rapidly absorbed from the gastrointestinal tract. Bioavailability is approximately 70-80%.
Metabolism
Metabolized in the liver to a limited extent.
Side Effects
Contraindications
- •Hypersensitivity to ciprofloxacin or other quinolones
- •Tendinitis or tendon rupture associated with quinolone use
Drug Interactions
Warfarin
May increase the anticoagulant effect of warfarin.
Theophylline
May increase theophylline levels, leading to toxicity.
Storage
Store at room temperature, away from moisture and direct sunlight.
Overdose
Symptoms of overdose may include nausea, vomiting, abdominal pain, and seizures. Treatment is supportive and symptomatic.
Pregnancy & Lactation
Ciprofloxacin should be avoided during pregnancy unless the benefit justifies the potential risk to the fetus. Use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Pharmacies and hospitals
Approval Status
DGDA Approved
Patent Status
Off-Patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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