Aritax
Generic Name
Aritax-6-mg-injection
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| aritax 6 mg injection | ৳ 5,330.00 | N/A |
Description
Overview of the medicine
Aritax-6-mg-injection is a biological agent used to modulate the immune system for certain chronic inflammatory or autoimmune conditions, aiming to reduce inflammation and disease progression.
Uses & Indications
Dosage
Adults
6 mg administered via subcutaneous injection once every 2 weeks.
Elderly
No specific dose adjustment is required for elderly patients (≥65 years), but careful monitoring for adverse effects is recommended.
Renal_impairment
No dose adjustment is necessary for patients with renal impairment, as the drug is not primarily cleared by the kidneys.
How to Take
Aritax-6-mg-injection is for subcutaneous use only. It should be administered into the thigh, abdomen, or upper arm. Patients should be instructed to rotate injection sites to prevent local reactions.
Mechanism of Action
This medicine acts on specific cellular pathways or receptors to regulate immune responses, thereby reducing inflammation and slowing down the progression of immune-mediated diseases.
Pharmacokinetics
Onset
Initial therapeutic effects may be observed within weeks, with full clinical benefits typically becoming apparent after several months of consistent treatment.
Excretion
Primarily cleared through the reticuloendothelial system and cellular degradation pathways, with minimal intact drug excreted renally.
Half life
The elimination half-life is approximately 2 to 4 weeks, typical for many biologic agents.
Absorption
Administered via subcutaneous (SC) injection, it is slowly absorbed into the systemic circulation. Bioavailability ranges from 70% to 80%.
Metabolism
Like other protein-based therapies, it is catabolized into small peptides and amino acids through general protein degradation pathways, rather than cytochrome P450 enzymes.
Side Effects
Contraindications
- •Known hypersensitivity to the active substance Aritax-6-mg-injection or any of its excipients.
- •Patients with active, severe infections, including localized infections.
Drug Interactions
Live Vaccines
Concurrent administration of live vaccines is not recommended due to the increased risk of infection.
Other Immunosuppressants
The concomitant use of other immunosuppressive agents may increase the risk of infections and myelosuppression.
Storage
Store in a refrigerator (2°C to 8°C). Do not freeze. Protect from light. Keep out of reach of children.
Overdose
In the event of an overdose, there is no specific antidote. Treatment should consist of symptomatic and supportive care, with close monitoring of vital signs and for any signs of adverse reactions.
Pregnancy & Lactation
Use during pregnancy or lactation should only be considered if the potential benefit justifies the potential risk to the fetus or infant. It is advisable to consult a physician for individual risk assessment.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
30 months from the date of manufacture when stored under recommended conditions.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Patent Pending
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