Arromin
Generic Name
Arromin 5 mg Oral Solution
Manufacturer
PharmaCorp Innovations Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| arromin 5 mg oral solution | ৳ 9.00 | N/A |
Description
Overview of the medicine
Arromin 5 mg Oral Solution is a medication used for the treatment of major depressive disorder. It helps to restore the balance of certain natural substances in the brain.
Uses & Indications
Dosage
Adults
Initial dose 5 mg once daily, may be increased to 10 mg after one week based on response and tolerability. Maximum dose 20 mg/day.
Elderly
Starting dose 2.5 mg once daily, careful titration to 5 mg if needed. Maximum 10 mg/day due to increased sensitivity.
Renal_impairment
No dose adjustment needed for mild to moderate impairment. Use with caution in severe impairment; consider 2.5 mg once daily.
How to Take
Take orally, with or without food, usually once daily in the morning or evening. Use the provided measuring device for accurate dosing.
Mechanism of Action
Arromin is a Serotonin-Norepinephrine Modulator. It selectively increases the levels of serotonin and norepinephrine in the brain by inhibiting their reuptake, thereby enhancing mood and reducing symptoms of depression.
Pharmacokinetics
Onset
Clinical effects typically observed within 2-4 weeks of continuous treatment.
Excretion
Excreted mainly through urine as metabolites.
Half life
Approximately 18-24 hours.
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver via CYP2D6 and CYP3A4 pathways.
Side Effects
Contraindications
- •Hypersensitivity to Arromin or any of its excipients
- •Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing MAOIs
- •Severe hepatic impairment
Drug Interactions
MAOIs
May lead to serotonin syndrome, potentially fatal.
NSAIDs
Increased risk of gastrointestinal bleeding.
Warfarin
Potentiation of anticoagulant effect, increased bleeding risk.
SSRIs/SNRIs
Increased risk of serotonin syndrome.
Tricyclic Antidepressants (TCAs)
Increased plasma levels of TCAs.
Storage
Store below 30°C, protected from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms include drowsiness, nausea, vomiting, dizziness, tachycardia. Treatment is symptomatic and supportive; maintain airway, monitor cardiac function, and vital signs.
Pregnancy & Lactation
Limited data on use during pregnancy; use only if potential benefit outweighs risk. Excreted in breast milk, consult doctor before breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Available in retail pharmacies and hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Under patent protection
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Global Brand Names
International brand names for this medicine
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