Artoflex
Generic Name
Curcumin Extract
Manufacturer
Medicare Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| artoflex 300 mg tablet | ৳ 4.02 | ৳ 40.20 |
Description
Overview of the medicine
Artoflex 300 mg Tablet is a dietary supplement containing Curcumin Extract, standardized for curcuminoids. It is used to support joint health, reduce inflammation, and provide antioxidant benefits.
Uses & Indications
Dosage
Adults
1 tablet (300 mg) once or twice daily, preferably with meals, or as directed by a healthcare professional.
Elderly
No specific dose adjustment required; adult dose typically applies.
Renal_impairment
Use with caution. Consult a physician for advice, though typically not renally cleared significantly.
How to Take
Take orally with a glass of water, preferably with a meal to enhance absorption and reduce potential gastric discomfort.
Mechanism of Action
Curcumin acts by inhibiting various inflammatory pathways, including NF-κB, COX-2, and LOX. It also exhibits potent antioxidant effects by scavenging free radicals and enhancing endogenous antioxidant enzyme activity.
Pharmacokinetics
Onset
Weeks to months for significant symptomatic relief in chronic conditions.
Excretion
Primarily via feces, with minor urinary excretion.
Half life
Short, typically 2-4 hours, due to rapid metabolism and excretion.
Absorption
Poor oral bioavailability, enhanced by piperine or lipid-based formulations. Peak plasma concentrations reached within 1-2 hours.
Metabolism
Extensive hepatic and intestinal metabolism (glucuronidation and sulfation).
Side Effects
Contraindications
- Known hypersensitivity to curcumin or any component of the tablet
- Bile duct obstruction
- Gallstones (use with caution)
Drug Interactions
Diabetes medications
May enhance the effect of blood sugar lowering medications.
Stomach acid reducers
May reduce curcumin absorption.
Anticoagulants/Antiplatelets
May increase the risk of bleeding.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Overdose symptoms may include increased gastrointestinal discomfort. Management is supportive and symptomatic.
Pregnancy & Lactation
Consult a healthcare professional before use during pregnancy or lactation due to insufficient data on safety. Generally considered safe in food amounts, but therapeutic doses are not well-studied.
Side Effects
Contraindications
- Known hypersensitivity to curcumin or any component of the tablet
- Bile duct obstruction
- Gallstones (use with caution)
Drug Interactions
Diabetes medications
May enhance the effect of blood sugar lowering medications.
Stomach acid reducers
May reduce curcumin absorption.
Anticoagulants/Antiplatelets
May increase the risk of bleeding.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Overdose symptoms may include increased gastrointestinal discomfort. Management is supportive and symptomatic.
Pregnancy & Lactation
Consult a healthcare professional before use during pregnancy or lactation due to insufficient data on safety. Generally considered safe in food amounts, but therapeutic doses are not well-studied.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Available in pharmacies and health stores
Approval Status
Approved as Dietary Supplement/OTC
Patent Status
Proprietary formulation
Clinical Trials
Numerous clinical trials support curcumin's efficacy in reducing inflammation and improving symptoms in osteoarthritis. Ongoing research explores its role in other inflammatory conditions and diseases.
Lab Monitoring
- None routinely required. Liver function tests may be considered in patients with pre-existing liver conditions or on long-term very high doses.
Doctor Notes
- Advise patients on realistic expectations regarding onset of action (slow-acting).
- Emphasize lifestyle modifications alongside supplement use for optimal joint health.
- Monitor for potential interactions, especially with anticoagulants.
Patient Guidelines
- Do not exceed the recommended dose.
- Inform your doctor about all other medications and supplements you are taking.
- Store in a cool, dry place away from direct sunlight.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally, Artoflex 300 mg Tablet does not affect the ability to drive or operate machinery. However, if you experience dizziness or any other side effect, avoid such activities.
Lifestyle Advice
- Maintain a balanced diet and regular exercise to support joint health.
- Manage weight to reduce stress on joints.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.