Ascoril LS Syrup
Generic Name
Ambroxol, Guaifenesin, Levosalbutamol
Manufacturer
Glenmark Pharmaceuticals Ltd.
Country
India
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Description
Overview of the medicine
Ascoril LS Syrup is a combination medicine used to relieve cough associated with bronchitis, asthma and upper respiratory tract infections.
Uses & Indications
Dosage
Adults
10ml three times a day
Elderly
Use with caution, as directed by physician.
Renal_impairment
Dose adjustment may be required in severe renal impairment.
How to Take
Oral administration, with or without food.
Mechanism of Action
Ambroxol is a mucolytic which thins and loosens mucus to clear congestion. Guaifenesin is an expectorant which decreases the stickiness of mucus. Levosalbutamol is a bronchodilator which relaxes the muscles of the airways and widens the airways.
Pharmacokinetics
Onset
Within 30 minutes.
Excretion
Renal excretion.
Half life
Ambroxol: 1-2 hours, Guaifenesin: 1 hour, Levosalbutamol: 3-4 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Hepatic metabolism.
Side Effects
Contraindications
- Hypersensitivity to any of the ingredients.
- Severe cardiovascular disorders.
Drug Interactions
Beta-blockers
May antagonize the bronchodilating effect of levosalbutamol.
MAO inhibitors
May increase the risk of cardiovascular side effects.
Storage
Store in a cool, dry place, away from direct sunlight.
Overdose
Symptoms of overdose may include tremor, headache, and tachycardia. Seek immediate medical attention.
Pregnancy & Lactation
Consult a doctor before using this medicine if you are pregnant or breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies and drug stores
Approval Status
DGDA Approved
Patent Status
Off-Patent
Clinical Trials
Clinical trials have demonstrated the efficacy of this combination in relieving cough and improving respiratory function.
Lab Monitoring
- Liver function tests
- Electrolyte levels
Doctor Notes
- Monitor patients for signs of cardiovascular side effects.
- Consider dose adjustments in patients with renal or hepatic impairment.
Patient Guidelines
- Take the medicine as prescribed by your doctor.
- Drink plenty of fluids to help loosen mucus.
- Avoid smoking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness; use caution when driving or operating machinery.
Lifestyle Advice
- Avoid exposure to allergens and irritants.
- Get regular exercise.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.