Avator-X
Generic Name
Avator
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Description
Overview of the medicine
Avator is a novel broad-spectrum antibiotic indicated for various bacterial infections. It works by inhibiting bacterial protein synthesis.
Uses & Indications
Dosage
Adults
500 mg once daily for 7-14 days, depending on infection severity.
Elderly
No specific dose adjustment required unless severe renal impairment.
Renal_impairment
For CrCl < 30 mL/min, reduce dose to 250 mg once daily.
How to Take
Can be taken with or without food. Swallow tablets whole with water.
Mechanism of Action
Avator binds to the 50S ribosomal subunit, thereby inhibiting bacterial protein synthesis and preventing bacterial growth.
Pharmacokinetics
Onset
Within 1-2 hours
Excretion
Mainly renal excretion (60-70% unchanged drug), with some biliary excretion.
Half life
Approximately 4-6 hours
Absorption
Rapidly absorbed from the gastrointestinal tract; bioavailability is approximately 80-90%.
Metabolism
Primarily hepatic metabolism via CYP450 enzymes (e.g., CYP3A4).
Side Effects
Contraindications
- •Hypersensitivity to Avator or any component of the formulation.
- •History of severe allergic reactions to other antibiotics of the same class.
Drug Interactions
Warfarin
May potentiate anticoagulant effects; monitor INR closely.
Antacids containing aluminum or magnesium
May decrease Avator absorption; administer at least 2 hours apart.
Storage
Store below 30°C in a dry place, away from direct light and moisture.
Overdose
In case of overdose, symptomatic and supportive measures should be taken. Gastric lavage may be considered.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and potential benefits outweigh risks. Caution is advised during lactation; consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Under patent protection
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Global Brand Names
International brand names for this medicine
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