Avelox
Generic Name
Moxifloxacin
Manufacturer
Bayer
Country
Germany
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| avelox 500 mg tablet | ৳ 12.00 | N/A |
Description
Overview of the medicine
Avelox is a fluoroquinolone antibiotic used to treat bacterial infections.
Uses & Indications
Dosage
Adults
400 mg orally once daily for 5-10 days, depending on the infection.
Elderly
Same as adult dosage; no dosage adjustment is generally needed.
Renal_impairment
No dosage adjustment is required in patients with renal impairment.
How to Take
Can be taken with or without food.
Mechanism of Action
Inhibits bacterial topoisomerase IV and DNA gyrase, enzymes required for DNA replication, transcription, repair, and recombination.
Pharmacokinetics
Onset
Within 1-2 hours
Excretion
Approximately 20% is excreted in urine as unchanged drug and approximately 25% is excreted in feces as unchanged drug.
Half life
Approximately 12 hours
Absorption
Rapidly and almost completely absorbed. Absolute bioavailability is approximately 90%.
Metabolism
Metabolized via glucuronide and sulfate conjugation
Side Effects
Contraindications
- Hypersensitivity to moxifloxacin or other quinolones
- Tendon disorders related to quinolone use
Drug Interactions
Warfarin
May increase the anticoagulant effect of warfarin.
Antacids containing aluminum or magnesium
May decrease moxifloxacin absorption.
Storage
Store at room temperature, away from moisture and heat.
Overdose
In the event of an overdose, supportive care should be provided.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Not recommended during breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Pharmacies and hospitals
Approval Status
FDA Approved/DGDA Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have established the efficacy of moxifloxacin in treating various bacterial infections.
Lab Monitoring
- Liver function tests
- Renal function tests
Doctor Notes
- Consider potential drug interactions before prescribing.
- Monitor patients for signs of tendon pain or swelling.
Patient Guidelines
- Take the medication as prescribed.
- Complete the full course of treatment.
- Report any unusual side effects to your doctor.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at once.
Driving Precautions
May cause dizziness or lightheadedness. Use caution while driving or operating machinery.
Lifestyle Advice
- Stay hydrated
- Avoid excessive sun exposure
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.