B-50 Forte
Generic Name
B-complex vitamins (High Potency)
Manufacturer
Generic/Multiple Manufacturers (e.g., Square Pharmaceuticals, Beximco Pharma, etc. in Bangladesh)
Country
Varies by manufacturer, commonly Bangladesh, India, USA
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| b 50 forte 5 mg capsule | ৳ 1.75 | ৳ 17.50 |
Description
Overview of the medicine
B-50 Forte 5 mg Capsule is a high-potency multivitamin supplement containing a comprehensive blend of essential B-complex vitamins. These vitamins play crucial roles in cellular metabolism, energy production, nervous system function, and overall health. The '5 mg' often refers to the folic acid content, which is vital for DNA synthesis and red blood cell formation.
Uses & Indications
Dosage
Adults
Usually 1 capsule daily, or as directed by a physician. Doses may vary based on individual needs and deficiency severity.
Elderly
Same as adult dosage, unless specific renal or hepatic impairment considerations are present. Physician consultation recommended.
Renal_impairment
Generally safe, but extreme caution with very high doses in severe renal impairment. Consultation with a healthcare professional is advised.
How to Take
Take orally with water, preferably with a meal to enhance absorption and minimize gastrointestinal upset.
Mechanism of Action
B vitamins act as coenzymes in various metabolic pathways. Thiamine (B1) is essential for carbohydrate metabolism. Riboflavin (B2) is involved in cellular respiration. Niacinamide (B3) plays a role in energy transfer reactions. Pantothenic acid (B5) is a component of coenzyme A, crucial for fatty acid synthesis and degradation. Pyridoxine (B6) is involved in amino acid metabolism. Biotin (B7) is a coenzyme for carboxylase enzymes. Folic acid (B9) is vital for nucleotide synthesis and homocysteine metabolism. Cyanocobalamin (B12) is necessary for red blood cell formation and neurological function.
Pharmacokinetics
Onset
Effects are generally gradual, noticeable over days to weeks of consistent supplementation.
Excretion
Primarily excreted renally (via urine). Excess amounts beyond physiological needs are readily eliminated.
Half life
Varies significantly for each B vitamin, generally short (hours to days) as they are water-soluble and not stored extensively, except for B12 which has a longer storage in the liver.
Absorption
Water-soluble B vitamins are readily absorbed from the gastrointestinal tract, primarily in the small intestine. Absorption can be affected by certain medical conditions or medications.
Metabolism
Metabolized in various tissues, primarily the liver, into their active coenzyme forms.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Leber's disease (due to Cyanocobalamin content)
Drug Interactions
Levodopa
Pyridoxine (B6) can decrease the effectiveness of Levodopa (used in Parkinson's disease) by enhancing its peripheral metabolism. This interaction is usually only clinically significant with very high doses of pyridoxine.
Phenobarbital, Phenytoin
May increase the requirement for folic acid and other B vitamins.
Certain antibiotics (e.g., Tetracyclines, Chloramphenicol)
Can interfere with the absorption or metabolism of some B vitamins. Separate administration times may be advisable.
Storage
Store in a cool (below 30°C), dry place, away from light and moisture. Keep out of reach of children.
Overdose
Due to their water-soluble nature, B vitamins are generally considered safe even at higher doses, as excess amounts are readily excreted. However, extremely high doses of certain individual B vitamins (e.g., Pyridoxine) over prolonged periods can lead to toxicity (e.g., peripheral neuropathy). Symptoms of a general overdose are usually mild gastrointestinal upset. Symptomatic and supportive treatment is recommended.
Pregnancy & Lactation
Generally considered safe and beneficial during pregnancy and lactation, especially folic acid and B12, which are crucial for fetal development and maternal health. However, always consult a healthcare professional before taking any supplement during these periods.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Leber's disease (due to Cyanocobalamin content)
Drug Interactions
Levodopa
Pyridoxine (B6) can decrease the effectiveness of Levodopa (used in Parkinson's disease) by enhancing its peripheral metabolism. This interaction is usually only clinically significant with very high doses of pyridoxine.
Phenobarbital, Phenytoin
May increase the requirement for folic acid and other B vitamins.
Certain antibiotics (e.g., Tetracyclines, Chloramphenicol)
Can interfere with the absorption or metabolism of some B vitamins. Separate administration times may be advisable.
Storage
Store in a cool (below 30°C), dry place, away from light and moisture. Keep out of reach of children.
Overdose
Due to their water-soluble nature, B vitamins are generally considered safe even at higher doses, as excess amounts are readily excreted. However, extremely high doses of certain individual B vitamins (e.g., Pyridoxine) over prolonged periods can lead to toxicity (e.g., peripheral neuropathy). Symptoms of a general overdose are usually mild gastrointestinal upset. Symptomatic and supportive treatment is recommended.
Pregnancy & Lactation
Generally considered safe and beneficial during pregnancy and lactation, especially folic acid and B12, which are crucial for fetal development and maternal health. However, always consult a healthcare professional before taking any supplement during these periods.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, drugstores, supermarkets
Approval Status
Generally Recognized As Safe (GRAS) by FDA, widely available without prescription.
Patent Status
No longer patented (generic formulations available)
Clinical Trials
Specific clinical trials for 'B-50 Forte 5 mg capsule' are rare as it's a vitamin supplement. Efficacy of individual B vitamins and B-complex formulations in treating deficiencies is well-established through numerous studies.
Lab Monitoring
- No routine lab monitoring is required for typical supplementation. In cases of suspected deficiency or malabsorption, specific B vitamin levels (e.g., B12, folate) may be tested.
Doctor Notes
- Emphasize the importance of B vitamins for nerve health and energy.
- Advise patients that urine discoloration is normal.
- Counsel patients on potential interactions, especially with Levodopa.
Patient Guidelines
- Take as directed, do not exceed recommended dose.
- Inform your doctor about all medications and supplements you are taking.
- Store in a cool, dry place away from direct sunlight.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it's almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
B-50 Forte 5 mg Capsule is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet to ensure adequate nutrient intake.
- Regular exercise and stress management can enhance overall health and nutrient utilization.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.