B-50 Forte
Generic Name
Vitamin B-complex
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| b 50 forte 5 mg syrup | ৳ 62.19 | N/A |
Description
Overview of the medicine
B-50 Forte Syrup is a high-potency Vitamin B-complex formulation designed to prevent and treat deficiencies of B vitamins. These vitamins are crucial for various metabolic processes, nerve function, red blood cell formation, and overall health.
Uses & Indications
Dosage
Adults
Typically 5-10 mL (1-2 teaspoonfuls), 2-3 times daily, or as directed by a physician.
Elderly
Standard adult dosage, no specific adjustment typically needed unless severe renal impairment is present. Use with caution in very high doses.
Children
2.5-5 mL (½-1 teaspoonful), 1-2 times daily, or as directed by a physician, depending on age and severity of deficiency.
Renal_impairment
No specific dose adjustments for typical B-complex supplementation. Consult a physician for high-dose regimens.
How to Take
For oral administration. Can be taken with or without food. Measure dose accurately using a measuring spoon or cup.
Mechanism of Action
B vitamins act as coenzymes in numerous metabolic pathways, playing essential roles in energy production, DNA synthesis, red blood cell formation, and nerve impulse transmission. They help convert food into energy and maintain healthy tissues.
Pharmacokinetics
Onset
Therapeutic effects are gradual, corresponding to the correction of vitamin deficiencies. Noticeable improvements may take days to weeks.
Excretion
Excess B vitamins are primarily excreted unchanged or as metabolites in the urine.
Half life
Being water-soluble, B vitamins generally have relatively short half-lives and are not extensively stored in the body.
Absorption
B vitamins are readily absorbed from the gastrointestinal tract, primarily in the small intestine.
Metabolism
Individual B vitamins undergo various metabolic transformations, primarily in the liver, to their active coenzyme forms.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation.
- In cases of Leber's disease (due to Cyanocobalamin, Vitamin B12, content) without consulting a physician.
Drug Interactions
Levodopa
Pyridoxine (Vitamin B6) may reduce the therapeutic effect of levodopa (used in Parkinson's disease) if given without a peripheral decarboxylase inhibitor.
Folic Acid (high doses)
May mask the symptoms of Vitamin B12 deficiency.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Do not freeze.
Overdose
B vitamins are water-soluble and generally considered to have low toxicity. In cases of overdose, excess vitamins are typically excreted in the urine. Very high, prolonged doses of certain B vitamins (e.g., Pyridoxine) may lead to adverse effects like peripheral neuropathy. Treatment is generally symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe and often recommended as a supplement during pregnancy and lactation to meet increased nutritional demands. However, always consult a healthcare provider before use.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation.
- In cases of Leber's disease (due to Cyanocobalamin, Vitamin B12, content) without consulting a physician.
Drug Interactions
Levodopa
Pyridoxine (Vitamin B6) may reduce the therapeutic effect of levodopa (used in Parkinson's disease) if given without a peripheral decarboxylase inhibitor.
Folic Acid (high doses)
May mask the symptoms of Vitamin B12 deficiency.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Do not freeze.
Overdose
B vitamins are water-soluble and generally considered to have low toxicity. In cases of overdose, excess vitamins are typically excreted in the urine. Very high, prolonged doses of certain B vitamins (e.g., Pyridoxine) may lead to adverse effects like peripheral neuropathy. Treatment is generally symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe and often recommended as a supplement during pregnancy and lactation to meet increased nutritional demands. However, always consult a healthcare provider before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date, when stored correctly.
Availability
Available in pharmacies, drugstores, and some supermarkets
Approval Status
Generally approved and available OTC
Patent Status
Off-patent
Clinical Trials
Established vitamin formulations like B-complex typically do not undergo new clinical trials for efficacy, as their benefits in deficiency states are well-documented. Trials might focus on new delivery systems or specific populations.
Lab Monitoring
- Routine lab monitoring is not typically required for standard B-complex supplementation.
- Monitoring may be considered in severe deficiency states or malabsorption syndromes.
Doctor Notes
- Emphasize the role of B-complex in overall health and energy metabolism, especially in patients with dietary deficiencies or increased requirements.
- Advise patients about yellow discoloration of urine, which is a harmless side effect.
- Caution against excessive self-medication, especially with very high doses of individual B vitamins.
Patient Guidelines
- Take exactly as directed by your doctor or as indicated on the label.
- Do not exceed the recommended dose without consulting a healthcare professional.
- Inform your doctor if you experience any unusual or severe side effects.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
B-50 Forte Syrup is not known to impair the ability to drive or operate machinery. No specific precautions are required.
Lifestyle Advice
- Maintain a balanced diet rich in fruits, vegetables, and whole grains to naturally obtain essential vitamins.
- Avoid excessive alcohol consumption, as it can deplete B vitamins.
- Engage in regular physical activity for overall well-being.
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