Bepotas
Generic Name
Bepotastine
Manufacturer
MediCo Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| bepotas 15 eye drop | ৳ 320.00 | N/A |
Description
Overview of the medicine
Bepotastine 0.15% ophthalmic solution is a topical histamine H1-receptor antagonist indicated for the treatment of ocular itching associated with allergic conjunctivitis.
Uses & Indications
Dosage
Adults
One drop in the affected eye(s) twice daily.
Elderly
No specific dosage adjustment required for elderly patients.
Renal_impairment
No specific dosage adjustment required for renal impairment, as systemic absorption is minimal.
How to Take
For ophthalmic use only. Tilt head back, pull down lower eyelid to create a pouch. Instill one drop and close eye gently. Do not touch dropper tip to eye or any other surface.
Mechanism of Action
Bepotastine is a direct H1-receptor antagonist and inhibits the release of histamine from mast cells. It prevents histamine from binding to H1 receptors, thereby reducing itching and other allergic symptoms.
Pharmacokinetics
Onset
Rapid, within minutes.
Excretion
Primarily excreted via urine as unchanged drug.
Half life
Approximately 2-4 hours (systemic, but primary effect is local).
Absorption
Systemic absorption is minimal following topical ocular administration.
Metabolism
Primarily metabolized by cytochrome P450 enzymes (CYP3A4) in vitro, but systemic exposure is low.
Side Effects
Contraindications
- Hypersensitivity to bepotastine or any component of the formulation
Drug Interactions
Other eye drops
If using other ophthalmic medications, wait at least 5 minutes between administrations.
Storage
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children.
Overdose
Topical ophthalmic overdose is unlikely to lead to systemic toxicity. If overdose occurs, flush eye(s) with lukewarm water. Symptomatic and supportive treatment may be provided if significant ingestion occurs.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. It is not known whether bepotastine is excreted in human milk; use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to bepotastine or any component of the formulation
Drug Interactions
Other eye drops
If using other ophthalmic medications, wait at least 5 minutes between administrations.
Storage
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children.
Overdose
Topical ophthalmic overdose is unlikely to lead to systemic toxicity. If overdose occurs, flush eye(s) with lukewarm water. Symptomatic and supportive treatment may be provided if significant ingestion occurs.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. It is not known whether bepotastine is excreted in human milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 months (unopened). Discard 28 days after opening.
Availability
Pharmacies, Hospitals, Retail Drug Stores
Approval Status
FDA Approved
Patent Status
Generic available (Patent expired)
Clinical Trials
Clinical trials have demonstrated bepotastine 0.15% ophthalmic solution to be effective and well-tolerated in reducing ocular itching associated with allergic conjunctivitis, with rapid onset of action.
Lab Monitoring
- No specific lab monitoring is generally required for topical ophthalmic bepotastine.
Doctor Notes
- Advise patients on proper instillation technique to avoid contamination and maximize efficacy.
- Remind patients to remove contact lenses before application and wait 10 minutes before reinserting.
- Caution against prolonged use without medical advice.
Patient Guidelines
- Do not wear contact lenses if your eyes are red.
- Remove contact lenses before applying drops and wait at least 10 minutes before reinserting.
- Do not use for more than 72 hours if condition worsens or persists.
- Avoid touching the dropper tip to your eye or any other surface to prevent contamination.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra drops to make up for a missed dose.
Driving Precautions
Bepotastine ophthalmic solution may cause temporary blurred vision or other visual disturbances which may affect the ability to drive or operate machinery. If blurred vision occurs, wait until vision clears before driving or operating machinery.
Lifestyle Advice
- Minimize exposure to known allergens (e.g., pollen, dust mites, pet dander).
- Avoid rubbing eyes excessively.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.