Betamesal
Generic Name
Betamethasone 0.05% w/v & Salicylic Acid 2% w/v Scalp Lotion
Manufacturer
Generic Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| betamesal 005 2 scalp lotion | ৳ 150.00 | N/A |
Description
Overview of the medicine
Betamesal 0.05-2 Scalp Lotion is a topical corticosteroid combined with a keratolytic agent. It is used to treat inflammatory skin conditions of the scalp such as psoriasis and seborrheic dermatitis where hyperkeratosis is a prominent feature.
Uses & Indications
Dosage
Adults
Apply a thin film to the affected scalp area once or twice daily, or as directed by a physician. Treatment duration should generally not exceed 2-4 weeks without reassessment.
Elderly
Similar to adult dosage, use with caution. Consult a physician.
Renal_impairment
No specific dosage adjustment is required for topical application.
How to Take
For external use only. Apply a few drops to the affected areas of the scalp and gently rub in. Wash hands thoroughly after application.
Mechanism of Action
Betamethasone is a potent corticosteroid that exerts anti-inflammatory, antipruritic, and vasoconstrictive actions. Salicylic acid acts as a keratolytic, causing shedding of the outer layer of skin and enhancing the penetration of betamethasone.
Pharmacokinetics
Onset
Symptomatic improvement typically within a few days of initiation.
Excretion
Excreted mainly via urine, with some via feces, if systemically absorbed.
Half life
Not specifically determined for topical application; systemic absorption is minimal.
Absorption
Minimal systemic absorption through intact skin. Absorption may increase with extensive use, damaged skin, or occlusive dressings. Salicylic acid can be absorbed systemically.
Metabolism
Metabolized primarily in the skin and liver if significant systemic absorption occurs.
Side Effects
Contraindications
- Hypersensitivity to betamethasone, salicylic acid, or any component of the formulation.
- Viral infections of the skin (e.g., herpes simplex, varicella).
- Fungal infections (unless concomitant antifungal therapy is used).
- Bacterial infections (unless concomitant antibacterial therapy is used).
- Acne vulgaris, rosacea, perioral dermatitis.
- Vaccination reactions.
Drug Interactions
Anticoagulants
Salicylic acid, if absorbed systemically, may potentiate the effects of coumarin anticoagulants.
Systemic Salicylates
Increased risk of salicylate toxicity if salicylic acid is absorbed systemically from extensive topical use.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overuse or prolonged use may lead to systemic effects of corticosteroids (e.g., Cushing's syndrome, adrenal suppression) or salicylate toxicity (e.g., tinnitus, dizziness). Management involves symptomatic and supportive therapy.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit justifies the potential risk to the fetus or infant. Consult a physician.
Side Effects
Contraindications
- Hypersensitivity to betamethasone, salicylic acid, or any component of the formulation.
- Viral infections of the skin (e.g., herpes simplex, varicella).
- Fungal infections (unless concomitant antifungal therapy is used).
- Bacterial infections (unless concomitant antibacterial therapy is used).
- Acne vulgaris, rosacea, perioral dermatitis.
- Vaccination reactions.
Drug Interactions
Anticoagulants
Salicylic acid, if absorbed systemically, may potentiate the effects of coumarin anticoagulants.
Systemic Salicylates
Increased risk of salicylate toxicity if salicylic acid is absorbed systemically from extensive topical use.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overuse or prolonged use may lead to systemic effects of corticosteroids (e.g., Cushing's syndrome, adrenal suppression) or salicylate toxicity (e.g., tinnitus, dizziness). Management involves symptomatic and supportive therapy.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit justifies the potential risk to the fetus or infant. Consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Off-patent
Clinical Trials
Numerous clinical trials have established the efficacy and safety of betamethasone with salicylic acid in treating various hyperkeratotic and inflammatory dermatoses, including scalp psoriasis and seborrheic dermatitis.
Lab Monitoring
- No routine laboratory monitoring is typically required for topical use. Adrenal function tests may be considered in cases of prolonged or extensive use.
Doctor Notes
- Educate patients on proper application technique and duration of treatment.
- Advise patients about potential local and systemic side effects, especially with long-term or extensive use.
- Monitor for signs of skin atrophy, infection, or lack of response.
- Avoid use on the face, groin, or axillae due to increased risk of side effects.
Patient Guidelines
- For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes.
- Do not use on broken or infected skin unless directed by a physician.
- Do not apply to large areas of the body or for prolonged periods without medical advice.
- Do not cover the treated area with occlusive dressings (e.g., plastic wrap) unless specifically instructed by a doctor.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not double the dose.
Driving Precautions
Betamesal 0.05-2 Scalp Lotion is for topical use and is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good scalp hygiene.
- Avoid harsh shampoos or irritants on the scalp.
- Inform your doctor if your condition does not improve within 2-4 weeks or worsens.
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