Bilaten
Generic Name
Bilastine 20 mg tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| bilaten 20 mg tablet | ৳ 15.00 | ৳ 210.00 |
Description
Overview of the medicine
Bilastine is a non-sedating, long-acting H1-antihistamine indicated for the symptomatic treatment of allergic rhinoconjunctivitis (seasonal and perennial) and urticaria.
Uses & Indications
Dosage
Adults
20 mg once daily. It should be taken one hour before or two hours after intake of food or fruit juice.
Elderly
No dose adjustment is required for elderly patients.
Renal_impairment
No dose adjustment is required in patients with renal impairment.
How to Take
Take the tablet orally, on an empty stomach, typically one hour before or two hours after eating food or drinking fruit juice. Swallow with water.
Mechanism of Action
Bilastine acts as a selective peripheral H1-receptor antagonist. It prevents the binding of histamine to H1 receptors, thereby inhibiting the histamine-mediated effects such as vasodilation, increased capillary permeability, and itching.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Approximately 95% of the administered dose is excreted unchanged: 28.3% in urine and 66.5% in feces.
Half life
Approximately 14.5 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached within approximately 1.3 hours. Food and fruit juice significantly reduce its bioavailability.
Metabolism
Bilastine is not significantly metabolized in humans. It is not an inducer or inhibitor of CYP450 isoenzymes.
Side Effects
Contraindications
- •Hypersensitivity to the active substance bilastine or to any of the excipients.
Drug Interactions
Diltiazem
Increases plasma concentration of bilastine.
Ritonavir
Increases plasma concentration of bilastine.
Cyclosporine
Increases plasma concentration of bilastine.
Erythromycin
Increases plasma concentration of bilastine.
Ketoconazole
Increases plasma concentration of bilastine.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated. There is no specific antidote for bilastine. Gastric lavage and activated charcoal may be considered if ingestion is recent.
Pregnancy & Lactation
Limited data on use during pregnancy. Animal studies do not indicate direct or indirect harmful effects. Use only if clearly needed and advised by a doctor. Unknown whether bilastine is excreted in human breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies
Approval Status
DGDA approved
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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