Billi-Meltab
Generic Name
Montelukast
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| billi meltab 10 mg tablet | ৳ 15.00 | ৳ 225.00 |
Description
Overview of the medicine
Billi-Meltab 10 mg Tablet is a leukotriene receptor antagonist used to prevent asthma attacks and to relieve symptoms of allergic rhinitis.
Uses & Indications
Dosage
Adults
10 mg once daily, taken in the evening for asthma or allergic rhinitis. For exercise-induced bronchoconstriction, take at least 2 hours before exercise, not to be taken more than once daily.
Elderly
No dosage adjustment necessary.
Renal_impairment
No dosage adjustment necessary.
How to Take
Place the orally disintegrating tablet on the tongue and allow it to dissolve completely, then swallow. It can be taken with or without food. Do not chew or crush the tablet.
Mechanism of Action
Montelukast works by blocking leukotrienes, which are natural substances in the body that cause inflammation and tightening of airways in asthma, and also trigger allergy symptoms.
Pharmacokinetics
Onset
Improvement in symptoms usually seen within one day.
Excretion
Excreted primarily in feces (about 86%) via bile; <0.2% excreted in urine.
Half life
Plasma half-life is 2.7 to 5.5 hours.
Absorption
Rapidly absorbed after oral administration. Bioavailability is approximately 64%.
Metabolism
Extensively metabolized in the liver by cytochrome P450 enzymes (CYP3A4, CYP2C9, CYP2A6).
Side Effects
Contraindications
- Hypersensitivity to montelukast or any component of the tablet.
- Acute asthma attacks (not for rescue therapy).
Drug Interactions
Rifampin
May decrease the concentration of montelukast.
Phenobarbital
May decrease the concentration of montelukast.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek emergency medical attention. Symptoms may include abdominal pain, somnolence, thirst, headache, vomiting, and psychomotor hyperactivity.
Pregnancy & Lactation
Use during pregnancy only if clearly needed. Excreted in breast milk, caution is advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture
Availability
Available in pharmacies and hospitals
Approval Status
Approved by FDA (USA) and DGDA (Bangladesh)
Patent Status
Patent expired, generic versions available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated efficacy and safety for asthma and allergic rhinitis.
Lab Monitoring
- No routine lab monitoring required.
- Liver function tests if hepatic impairment is suspected.
Doctor Notes
- Remind patients that montelukast is not for acute attacks.
- Counsel on potential neuropsychiatric side effects.
- Advise patients to take dose consistently in the evening.
Patient Guidelines
- Take the tablet at the same time each day, preferably in the evening.
- Do not use for acute asthma attacks; use a fast-acting inhaler for relief.
- Report any mood changes or suicidal thoughts to your doctor immediately.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
May cause dizziness or drowsiness in some individuals. Exercise caution when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Avoid known allergens that trigger asthma or allergy symptoms.
- Maintain a healthy lifestyle, including regular exercise (if not exacerbating EIB) and a balanced diet.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.