Oral Rehydration Salt (Various Brands)
Generic Name
bio-oral-saline
Manufacturer
Various manufacturers worldwide
Country
Global
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Description
Overview of the medicine
Bio-Oral-Saline is an oral rehydration solution used to treat and prevent dehydration caused by diarrhea or other conditions involving fluid and electrolyte loss. It works by replacing lost fluids and essential salts, helping to restore the body's fluid balance.
Uses & Indications
Dosage
Adults
As per fluid loss, usually 200-400 ml after each loose stool. Max 2-4 liters/day.
Elderly
Same as adults, with careful monitoring for fluid overload in those with cardiac or renal issues.
Renal_impairment
Use with caution; electrolyte balance should be monitored, as it may exacerbate hyperkalemia or hypernatremia.
How to Take
Dissolve the contents of the sachet in the specified amount of clean drinking water (usually 250 ml for standard packets). Stir well and drink slowly in small sips. Do not boil the solution after mixing.
Mechanism of Action
Oral Rehydration Salts work based on the principle of glucose-sodium co-transport in the small intestine. Glucose enhances the absorption of sodium and water, helping to replenish lost fluids and electrolytes.
Pharmacokinetics
Onset
Within minutes to hours of oral administration.
Excretion
Excess water and electrolytes are excreted via kidneys.
Half life
Not applicable in the conventional sense for an electrolyte solution.
Absorption
Water and electrolytes are rapidly absorbed from the gastrointestinal tract due to the presence of glucose.
Metabolism
Electrolytes are not metabolized; glucose is metabolized for energy.
Side Effects
Contraindications
- •Severe dehydration requiring intravenous fluids
- •Persistent vomiting that prevents oral intake
- •Anuria (absence of urine formation)
- •Intestinal obstruction
Drug Interactions
Diuretics
May alter electrolyte balance; monitor carefully.
Drugs affecting kidney function
May increase risk of electrolyte imbalances.
Storage
Store in a cool, dry place, below 30°C. Protect from moisture and direct sunlight. Keep out of reach of children.
Overdose
Overdose is rare when prepared correctly. Symptoms may include hypernatremia (if prepared with too little water) or fluid overload in patients with pre-existing cardiac or renal conditions. Management involves correcting the underlying fluid and electrolyte imbalances.
Pregnancy & Lactation
Safe to use during pregnancy and lactation. It is crucial for maintaining hydration in pregnant and breastfeeding women experiencing fluid loss.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years for unopened powder sachets.
Availability
Pharmacies, supermarkets, healthcare facilities
Approval Status
Globally approved and widely used
Patent Status
Off-patent, generic
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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