Bionic
Generic Name
Bionic 100 mg Injection
Manufacturer
BioGen Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| bionic 100 mg injection | ৳ 25.00 | N/A |
Description
Overview of the medicine
Bionic-100 mg Injection is a synthetic biologic agent designed to enhance the body's immune response, particularly in conditions of immunodeficiency or chronic infections. It helps in restoring and modulating immune functions.
Uses & Indications
Dosage
Adults
100 mg administered intramuscularly or subcutaneously once daily, or every other day, depending on the severity of the condition and clinical response.
Elderly
No specific dose adjustment is generally required for elderly patients, but caution should be exercised due to potential age-related organ function decline. Monitor renal function closely.
Renal_impairment
For patients with moderate to severe renal impairment (CrCl < 50 mL/min), a reduced dose of 50 mg every other day may be considered, with careful monitoring of immune markers.
How to Take
Bionic-100 mg Injection should be administered by a healthcare professional, either intramuscularly (into a large muscle like the gluteus or deltoid) or subcutaneously (into the abdomen, thigh, or upper arm).
Mechanism of Action
Bionic-100 mg acts by stimulating various components of the immune system, including T-lymphocytes and natural killer cells. It promotes the production of cytokines, enhancing overall cellular and humoral immunity to combat pathogens effectively.
Pharmacokinetics
Onset
Immunomodulatory effects typically begin within 24-48 hours of initial administration.
Excretion
The degradation products are excreted primarily via the renal pathway.
Half life
The elimination half-life is approximately 30 hours, allowing for once-daily or alternate-day dosing.
Absorption
Rapidly absorbed after intramuscular or subcutaneous administration, reaching peak plasma concentrations within 1-2 hours. Bioavailability is approximately 90%.
Metabolism
Metabolized by proteolytic degradation into smaller peptides and amino acids, primarily within the reticuloendothelial system and other tissues.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients
- Known history of severe allergic reactions to immunoglobulins
- Certain uncontrolled autoimmune diseases where immunostimulation is contraindicated
Drug Interactions
Immunosuppressants
Concurrent use with immunosuppressants (e.g., corticosteroids, calcineurin inhibitors) may reduce the efficacy of Bionic-100 mg due to opposing immune effects. Careful monitoring and dose adjustment may be necessary.
Live Attenuated Vaccines
Bionic-100 mg may interfere with the immune response to live attenuated vaccines. Avoid administration of live vaccines for at least 3 months after the last dose of Bionic-100 mg.
Storage
Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Keep out of reach of children.
Overdose
There is no specific antidote for Bionic-100 mg overdose. Management should be supportive, focusing on symptomatic treatment and monitoring of vital signs. In cases of severe adverse reactions, discontinue the injection immediately.
Pregnancy & Lactation
Limited data on use in pregnancy. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is unknown whether Bionic-100 mg is excreted in human milk; use with caution during lactation.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients
- Known history of severe allergic reactions to immunoglobulins
- Certain uncontrolled autoimmune diseases where immunostimulation is contraindicated
Drug Interactions
Immunosuppressants
Concurrent use with immunosuppressants (e.g., corticosteroids, calcineurin inhibitors) may reduce the efficacy of Bionic-100 mg due to opposing immune effects. Careful monitoring and dose adjustment may be necessary.
Live Attenuated Vaccines
Bionic-100 mg may interfere with the immune response to live attenuated vaccines. Avoid administration of live vaccines for at least 3 months after the last dose of Bionic-100 mg.
Storage
Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Keep out of reach of children.
Overdose
There is no specific antidote for Bionic-100 mg overdose. Management should be supportive, focusing on symptomatic treatment and monitoring of vital signs. In cases of severe adverse reactions, discontinue the injection immediately.
Pregnancy & Lactation
Limited data on use in pregnancy. Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is unknown whether Bionic-100 mg is excreted in human milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture when stored under recommended conditions.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Patent Protected
Clinical Trials
Ongoing Phase III and IV clinical trials are evaluating the long-term efficacy and safety profile of Bionic-100 mg in broader patient populations and for new indications.
Lab Monitoring
- Complete Blood Count (CBC) with differential
- Immunoglobulin levels
- Renal function tests (e.g., creatinine, BUN)
- Liver function tests (LFTs) periodically
Doctor Notes
- Ensure patient is screened for pre-existing autoimmune conditions.
- Monitor for signs of infusion reactions during initial doses.
- Educate patient on proper self-administration technique if applicable.
Patient Guidelines
- Always use this medicine exactly as your doctor has told you.
- Do not stop the treatment without consulting your doctor.
- Report any unusual or severe side effects immediately to your healthcare provider.
- Ensure proper storage of the injection as instructed.
Missed Dose Advice
If a dose is missed, administer it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
Bionic-100 mg may cause dizziness or fatigue in some patients. If you experience these symptoms, avoid driving or operating machinery until you feel well.
Lifestyle Advice
- Maintain a healthy and balanced diet.
- Ensure adequate hydration during treatment.
- Avoid crowded places if your immune system is compromised.
- Discuss with your doctor about exercise routines.
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