Calac
Generic Name
Calcium Carbonate
Manufacturer
MediCorp Pharma
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| calac 300 mg tablet | ৳ 0.50 | ৳ 5.00 |
Description
Overview of the medicine
Calac 300 mg Tablet contains Calcium Carbonate, a mineral essential for maintaining healthy bones, teeth, and overall body function. It is used to prevent or treat calcium deficiencies and as an antacid.
Uses & Indications
Dosage
Adults
For calcium supplementation: 1-2 tablets (300-600 mg elemental calcium) 2-3 times daily, with meals. As antacid: 1-2 tablets as needed, up to 7 tablets daily.
Elderly
Similar to adult dosage, but caution with renal function. Consult a doctor for specific guidance.
Renal_impairment
Use with caution. Dosage adjustments may be necessary due to risk of hypercalcemia. Regular monitoring of serum calcium is recommended.
How to Take
Take orally, preferably with food to enhance absorption. If used as an antacid, it can be taken after meals or at bedtime. Drink plenty of water.
Mechanism of Action
Calcium Carbonate acts as a source of calcium to replenish deficiencies. As an antacid, it neutralizes stomach acid by reacting with hydrochloric acid to form calcium chloride, water, and carbon dioxide.
Pharmacokinetics
Onset
Antacid effect: within minutes. Systemic calcium replenishment: hours to days.
Excretion
Primarily renally (via urine), with some excretion in feces (unabsorbed calcium).
Half life
Variable, as calcium homeostasis is tightly regulated. Biological half-life in bone is very long.
Absorption
Absorbed in the small intestine, primarily through active transport and passive diffusion. Requires Vitamin D for optimal absorption.
Metabolism
Not metabolized in the liver; elemental calcium is incorporated into bone and used by tissues.
Side Effects
Contraindications
- Hypercalcemia (high calcium levels in blood)
- Severe renal impairment
- Hypersensitivity to calcium carbonate or any component of the formulation
Drug Interactions
Bisphosphonates
May impair absorption of bisphosphonates; separate administration by at least 30-60 minutes.
Iron Supplements
May reduce iron absorption; separate administration by at least 2 hours.
Thiazide Diuretics
May increase risk of hypercalcemia.
Digitalis Glycosides
May increase the risk of digitalis toxicity in hypercalcemia.
Tetracyclines & Quinolones
May reduce absorption of these antibiotics; separate administration by at least 2-4 hours.
Thyroid Hormones (e.g., Levothyroxine)
May reduce absorption of thyroid hormones; separate administration by at least 4 hours.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include severe constipation, nausea, vomiting, confusion, increased thirst, and frequent urination. In severe cases, it can lead to hypercalcemia, kidney stones, and milk-alkali syndrome. Management involves discontinuing calcium intake, ensuring adequate hydration, and supportive care. Medical attention is required.
Pregnancy & Lactation
Calcium is essential during pregnancy and lactation. This medicine is generally considered safe when taken at recommended doses under medical supervision. Consult your doctor.
Side Effects
Contraindications
- Hypercalcemia (high calcium levels in blood)
- Severe renal impairment
- Hypersensitivity to calcium carbonate or any component of the formulation
Drug Interactions
Bisphosphonates
May impair absorption of bisphosphonates; separate administration by at least 30-60 minutes.
Iron Supplements
May reduce iron absorption; separate administration by at least 2 hours.
Thiazide Diuretics
May increase risk of hypercalcemia.
Digitalis Glycosides
May increase the risk of digitalis toxicity in hypercalcemia.
Tetracyclines & Quinolones
May reduce absorption of these antibiotics; separate administration by at least 2-4 hours.
Thyroid Hormones (e.g., Levothyroxine)
May reduce absorption of thyroid hormones; separate administration by at least 4 hours.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include severe constipation, nausea, vomiting, confusion, increased thirst, and frequent urination. In severe cases, it can lead to hypercalcemia, kidney stones, and milk-alkali syndrome. Management involves discontinuing calcium intake, ensuring adequate hydration, and supportive care. Medical attention is required.
Pregnancy & Lactation
Calcium is essential during pregnancy and lactation. This medicine is generally considered safe when taken at recommended doses under medical supervision. Consult your doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months from manufacturing date
Availability
Available in pharmacies and supermarkets
Approval Status
Approved by regulatory authorities (e.g., DGDA, FDA)
Patent Status
Off-patent
Clinical Trials
Numerous clinical trials have established the efficacy of calcium carbonate in preventing and treating calcium deficiencies, osteoporosis, and as an antacid. Ongoing research focuses on optimal dosing and combinations.
Lab Monitoring
- Serum calcium levels (especially for long-term use or in patients with renal impairment)
- Renal function tests
Doctor Notes
- Advise patients to take Calac 300 mg with meals for better absorption.
- Monitor serum calcium and renal function, especially in patients on concomitant medications or with pre-existing conditions.
- Educate patients on potential drug interactions, particularly with antibiotics and thyroid hormones.
Patient Guidelines
- Take with food to improve absorption and reduce gastric upset.
- Ensure adequate fluid intake to prevent constipation.
- Do not take other calcium-containing supplements or antacids without consulting your doctor.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Calac 300 mg Tablet is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and Vitamin D.
- Engage in regular weight-bearing exercise for bone health.
- Avoid excessive intake of caffeine, alcohol, and sodium, which can increase calcium excretion.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.