Calboplex
Generic Name
Calcium Carbonate, Vitamin D3, Multivitamin & Multimineral complex
Manufacturer
MediCare Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| calboplex tablet | ৳ 6.00 | N/A |
Description
Overview of the medicine
Calboplex Tablet is a comprehensive nutritional supplement containing calcium, vitamin D3, and a blend of essential multivitamins and multiminerals. It is formulated to support bone health, boost immunity, and maintain overall bodily functions.
Uses & Indications
Dosage
Adults
Typically 1-2 tablets daily, preferably after meals, or as directed by the physician.
Elderly
Same as adult dosage, or as advised by a healthcare professional, considering individual needs.
Renal_impairment
Use with caution and consult a physician; dose adjustment may be necessary in severe impairment due to potential for hypercalcemia or accumulation of certain minerals.
How to Take
Orally, swallow whole with water. It is best taken after meals to enhance absorption and minimize gastrointestinal upset.
Mechanism of Action
Calcium is crucial for bone formation and maintenance, nerve function, and muscle contraction. Vitamin D3 aids in calcium absorption from the gut and its deposition into bones. Other vitamins and minerals act as cofactors in various metabolic processes, supporting energy production, immune function, and cellular repair.
Pharmacokinetics
Onset
Long-term effect, not immediate. Clinical benefits may be observed after weeks to months of regular use.
Excretion
Primarily renal for water-soluble vitamins and minerals; some fat-soluble vitamins and calcium are excreted via bile.
Half life
Variable for each component. Vitamin D3 has a half-life of 24 hours for calcifediol, longer for storage forms.
Absorption
Varies depending on the specific vitamin/mineral; calcium absorption is enhanced by Vitamin D3, typically 20-30% of ingested calcium.
Metabolism
Each component undergoes specific metabolic pathways; Vitamin D3 is hydroxylated in the liver and kidneys to active forms.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Hypercalcemia (high calcium levels in blood)
- Severe renal impairment (without medical supervision)
- Hypervitaminosis D
Drug Interactions
Digoxin
High calcium levels can increase digoxin toxicity.
Levothyroxine
Calcium may impair absorption; separate administration by 4 hours.
Bisphosphonates
Separate administration to prevent reduced absorption.
Thiazide Diuretics
May increase risk of hypercalcemia.
Tetracyclines & Fluoroquinolones
Calcium can reduce absorption of these antibiotics; separate administration by at least 2-4 hours.
Storage
Store in a cool and dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, constipation, abdominal pain, muscle weakness, excessive thirst, increased urination, confusion. In severe cases, it can lead to hypercalcemia, renal impairment, and cardiac arrhythmias. Treatment involves discontinuing the supplement, hydration, and supportive care. Medical attention is required.
Pregnancy & Lactation
Generally considered safe and beneficial during pregnancy and lactation for appropriate supplementation, but should be used under medical advice to ensure proper dosing and avoid excessive intake.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies, drugstores, supermarkets
Approval Status
Approved by DGDA (Directorate General of Drug Administration, Bangladesh)
Patent Status
No active patent for generic formulation
Clinical Trials
Clinical trials have demonstrated efficacy in improving bone mineral density and correcting vitamin D deficiency. Ongoing studies explore its role in broader health outcomes.
Lab Monitoring
- Serum calcium levels (if concerned about hypercalcemia)
- Serum Vitamin D levels (to assess deficiency)
- Renal function tests (for patients with kidney issues)
Doctor Notes
- Advise patients to maintain adequate hydration.
- Emphasize not to exceed recommended dosage to avoid hypercalcemia.
- Review concomitant medications for potential interactions, especially with antibiotics and thyroid hormones.
Patient Guidelines
- Take as directed by your doctor or as per label instructions.
- Do not exceed the recommended daily dose.
- Inform your doctor about all other medications and supplements you are taking.
- Store in a cool, dry place away from direct sunlight and moisture.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to compensate for a missed one.
Driving Precautions
Calboplex Tablet is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and vitamin D sources.
- Engage in regular weight-bearing exercise to support bone health.
- Ensure adequate sun exposure for natural vitamin D synthesis, while protecting against sunburn.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.