Calbotol
Generic Name
Calbotol 1200 mg Tablet
Manufacturer
Apex Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| calbotol 1200 mg tablet | ৳ 13.00 | N/A |
Description
Overview of the medicine
Calbotol 1200 mg tablet is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever associated with various conditions.
Uses & Indications
Dosage
Adults
1200 mg once daily, or 600 mg twice daily, as directed by physician. Maximum daily dose is 1200 mg.
Elderly
Initiate with the lowest effective dose and monitor for adverse effects.
Renal_impairment
Dose adjustment required based on creatinine clearance; consult physician.
How to Take
To be taken orally, preferably with food or after a meal, to minimize gastrointestinal discomfort.
Mechanism of Action
It works by inhibiting the production of prostaglandins, which are substances in the body that cause pain, inflammation, and fever.
Pharmacokinetics
Onset
30-60 minutes
Excretion
Mainly excreted in urine as metabolites.
Half life
6-8 hours
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract.
Metabolism
Primarily metabolized in the liver by cytochrome P450 enzymes.
Side Effects
Contraindications
- History of peptic ulcer or gastrointestinal bleeding
- Severe renal or hepatic impairment
- Known hypersensitivity to Calbotol or other NSAIDs
- Third trimester of pregnancy
- Severe heart failure
Drug Interactions
Lithium
May increase lithium plasma levels.
Warfarin
Increases risk of bleeding.
Methotrexate
May increase methotrexate toxicity.
ACE inhibitors/Diuretics
May reduce antihypertensive effects and increase risk of renal impairment.
Storage
Store below 25°C in a dry and cool place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, lethargy, drowsiness. Management involves symptomatic treatment and supportive care. Gastric lavage or activated charcoal may be considered.
Pregnancy & Lactation
Avoid during the third trimester of pregnancy. Use with caution during other trimesters and lactation; consult a doctor.
Side Effects
Contraindications
- History of peptic ulcer or gastrointestinal bleeding
- Severe renal or hepatic impairment
- Known hypersensitivity to Calbotol or other NSAIDs
- Third trimester of pregnancy
- Severe heart failure
Drug Interactions
Lithium
May increase lithium plasma levels.
Warfarin
Increases risk of bleeding.
Methotrexate
May increase methotrexate toxicity.
ACE inhibitors/Diuretics
May reduce antihypertensive effects and increase risk of renal impairment.
Storage
Store below 25°C in a dry and cool place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, lethargy, drowsiness. Management involves symptomatic treatment and supportive care. Gastric lavage or activated charcoal may be considered.
Pregnancy & Lactation
Avoid during the third trimester of pregnancy. Use with caution during other trimesters and lactation; consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patent expired
Clinical Trials
Multiple clinical trials have been conducted to evaluate its efficacy and safety in the treatment of chronic musculoskeletal pain in adults.
Lab Monitoring
- Renal function tests (e.g., serum creatinine, BUN)
- Liver function tests (e.g., ALT, AST)
- Complete blood count (CBC) for long-term therapy
Doctor Notes
- Advise patients on gastroprotective measures, especially those at high risk for GI complications.
- Monitor renal and hepatic function periodically in patients on long-term therapy.
- Educate patients on potential cardiovascular risks associated with NSAID use.
Patient Guidelines
- Do not change the dose without consulting your doctor.
- Take with plenty of water.
- Report any unusual side effects promptly.
- Avoid concomitant use with other NSAIDs.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or drowsiness in some patients. Patients should be cautious when driving or operating machinery.
Lifestyle Advice
- Avoid driving or operating heavy machinery if experiencing dizziness or drowsiness.
- Limit alcohol consumption and smoking.
- Maintain a balanced diet and stay hydrated.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.