Canten
Generic Name
Clotrimazole 1% Cream
Manufacturer
Reputable Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| canten 1 cream | ৳ 29.00 | N/A |
Description
Overview of the medicine
Canten 1% Cream contains Clotrimazole, an antifungal medication used to treat a variety of skin infections caused by fungi, including athlete's foot, jock itch, ringworm, and other candidiasis.
Uses & Indications
Dosage
Adults
Apply a thin layer of cream to the affected skin area and surrounding areas 2 to 3 times daily. Gently rub in. Continue treatment for at least 2 to 4 weeks, even if symptoms improve.
Elderly
No specific dosage adjustment is required for elderly patients.
Renal_impairment
No dosage adjustment is required for patients with renal impairment as systemic absorption is minimal.
How to Take
Clean and dry the affected area thoroughly before applying the cream. Apply a thin layer of cream and gently massage until it is evenly distributed. Wash hands immediately after application.
Mechanism of Action
Clotrimazole works by inhibiting the biosynthesis of ergosterol, a crucial component of fungal cell membranes. This leads to structural and functional impairment of the fungal cytoplasmic membrane, resulting in leakage of intracellular contents and ultimately fungal cell death.
Pharmacokinetics
Onset
Symptomatic relief typically begins within a few days of starting treatment.
Excretion
Metabolites are primarily excreted in bile and urine.
Half life
Due to minimal systemic absorption, a systemic half-life is not clinically relevant for topical administration.
Absorption
When applied topically to intact or inflamed skin, clotrimazole is minimally absorbed systemically. Peak serum concentrations are usually below the detection limit.
Metabolism
Any systemically absorbed clotrimazole is rapidly metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Known hypersensitivity to clotrimazole or any other ingredients in the cream.
Drug Interactions
Topical Steroids
Concurrent use may reduce the effectiveness of clotrimazole; avoid if possible.
Amphotericin B or Nystatin (topical)
May antagonize the antifungal effects of clotrimazole.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects due to minimal absorption. In case of accidental oral ingestion, supportive measures should be taken.
Pregnancy & Lactation
While systemic absorption is minimal, consult a doctor before using Canten 1% Cream during pregnancy or breastfeeding. Use only if clearly needed and potential benefits outweigh risks.
Side Effects
Contraindications
- Known hypersensitivity to clotrimazole or any other ingredients in the cream.
Drug Interactions
Topical Steroids
Concurrent use may reduce the effectiveness of clotrimazole; avoid if possible.
Amphotericin B or Nystatin (topical)
May antagonize the antifungal effects of clotrimazole.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic effects due to minimal absorption. In case of accidental oral ingestion, supportive measures should be taken.
Pregnancy & Lactation
While systemic absorption is minimal, consult a doctor before using Canten 1% Cream during pregnancy or breastfeeding. Use only if clearly needed and potential benefits outweigh risks.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, Drug Stores
Approval Status
Approved (Generic)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Clotrimazole has been extensively studied in numerous clinical trials and has demonstrated consistent efficacy and safety for the treatment of various superficial fungal infections.
Lab Monitoring
- No routine lab monitoring is required for topical clotrimazole use.
Doctor Notes
- Ensure proper diagnosis of fungal infection before prescribing. Differentiate from bacterial or viral skin conditions.
- Educate patients on hygiene practices to prevent recurrence and spread.
- Advise patients to complete the full course of treatment, even if symptomatic relief occurs early, to prevent relapse.
Patient Guidelines
- For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes.
- Complete the full course of treatment, even if symptoms improve, to prevent recurrence.
- If there is no improvement after 4 weeks of treatment, consult your doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Canten 1% Cream has no known influence on the ability to drive or operate machinery.
Lifestyle Advice
- Keep the affected area clean and dry.
- Wear loose-fitting clothing made of natural fibers to allow air circulation.
- Avoid sharing towels, clothing, or personal items to prevent spread of infection.
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Global Brand Names
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