Caprolin
Generic Name
Caprolex
Manufacturer
PharmaCorp Bangladesh
Country
Bangladesh
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Description
Overview of the medicine
Caprolex is a hypothetical antidepressant medication of the Selective Serotonin Reuptake Inhibitor (SSRI) class. It is used to treat major depressive disorder, generalized anxiety disorder, and panic disorder. Please note that 'Caprolex' is not a recognized generic drug name and this entry is for illustrative purposes only.
Uses & Indications
Dosage
Adults
Initial dose 10 mg once daily, may be increased to 20 mg after one week. Maximum dose 20 mg daily.
Elderly
Initial dose 10 mg once daily. Max dose 10 mg daily due to potential increased sensitivity.
Renal_impairment
No dosage adjustment needed for mild to moderate renal impairment. Use with caution in severe impairment.
How to Take
Caprolex tablets should be taken orally once daily, with or without food, preferably in the morning.
Mechanism of Action
Caprolex is thought to work by inhibiting the reuptake of serotonin in the central nervous system, thereby increasing the concentration of serotonin in the synaptic cleft. This leads to an enhancement of serotonergic neurotransmission.
Pharmacokinetics
Onset
Antidepressant effects may take 2-4 weeks to manifest fully.
Excretion
Excreted mainly via urine as metabolites, with some fecal excretion.
Half life
Approximately 20-26 hours, allowing for once-daily dosing.
Absorption
Well absorbed orally; peak plasma concentrations reached within 4-8 hours.
Metabolism
Extensively metabolized in the liver, primarily by CYP enzymes.
Side Effects
Contraindications
- Hypersensitivity to Caprolex or any excipients
- Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing MAOI therapy
Drug Interactions
MAOIs
Risk of serotonin syndrome. Concomitant use is contraindicated.
NSAIDs
Increased risk of gastrointestinal bleeding.
Warfarin
May potentiate anticoagulant effects; monitor INR.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, dizziness, tremor, and somnolence. Management is supportive and symptomatic; ensure adequate airway, breathing, and circulation. Activated charcoal may be considered.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult a doctor. Not recommended during breastfeeding without medical advice.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Available in pharmacies and hospitals
Approval Status
Hypothetically Approved by Regulatory Authority
Patent Status
Hypothetically Patent Expired
Clinical Trials
Hypothetical clinical trials demonstrated efficacy in major depressive disorder and anxiety disorders with a tolerable safety profile.
Lab Monitoring
- Monitor renal and hepatic function periodically, especially in patients with pre-existing impairment.
- Monitor for hyponatremia, particularly in elderly patients or those on diuretics.
Doctor Notes
- Emphasize gradual titration of dosage during initiation and discontinuation.
- Monitor patients for clinical worsening and suicidality, especially at the beginning of treatment or after dose changes.
Patient Guidelines
- Do not stop taking Caprolex suddenly, as this can lead to withdrawal symptoms. Consult your doctor for a gradual reduction.
- It may take several weeks for Caprolex to start working, continue taking it as prescribed.
- Report any unusual mood changes or suicidal thoughts to your doctor immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.
Driving Precautions
Caprolex may cause dizziness or drowsiness. Patients should be cautious when driving or operating machinery until they know how the medication affects them.
Lifestyle Advice
- Maintain a healthy diet and regular exercise.
- Avoid excessive caffeine and alcohol.
- Practice stress-reduction techniques.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.