Carbate
Generic Name
carbate-100-mcg-injection
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| carbate 100 mcg injection | ৳ 150.00 | N/A |
Description
Overview of the medicine
Carbate 100 mcg Injection contains Carbazochrome, an antihemorrhagic agent used to control capillary bleeding by reducing capillary fragility and permeability. It helps to maintain the integrity of blood vessels.
Uses & Indications
Dosage
Adults
Typically 100 mcg (1 ampoule) administered intramuscularly or intravenously, once or twice daily, or as directed by the physician. Dosage may vary based on condition and severity.
Elderly
No specific dose adjustment is usually required, but caution is advised. Dosage should be determined by a physician.
Renal_impairment
No specific dose adjustment is generally needed for mild to moderate renal impairment. Consult a physician for severe impairment.
How to Take
Administer intramuscularly (IM) or intravenously (IV) by a healthcare professional. For IV administration, it should be given slowly.
Mechanism of Action
Carbazochrome works by increasing the resistance of capillaries and reducing their permeability, thereby stabilizing the capillary walls and decreasing extravasation of blood. It is believed to act on the vascular endothelium.
Pharmacokinetics
Onset
Relatively rapid onset of action.
Excretion
Primarily excreted via the kidneys.
Half life
Short half-life, typically a few hours.
Absorption
Rapidly absorbed after intramuscular (IM) administration.
Metabolism
Believed to be metabolized in the liver, though specific pathways are not extensively documented.
Side Effects
Contraindications
- Hypersensitivity to Carbazochrome or any component of the formulation.
Drug Interactions
Anticoagulants
Use with caution; Carbazochrome does not replace the need for specific anti-coagulant reversal strategies if bleeding is due to anticoagulant therapy. It primarily affects capillary integrity, not coagulation factors.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
In case of an overdose, symptomatic and supportive treatment should be initiated. There is no specific antidote.
Pregnancy & Lactation
Use in pregnancy and lactation only if clearly needed and after consulting a physician. Animal studies have not shown teratogenic effects, but human data are limited.
Side Effects
Contraindications
- Hypersensitivity to Carbazochrome or any component of the formulation.
Drug Interactions
Anticoagulants
Use with caution; Carbazochrome does not replace the need for specific anti-coagulant reversal strategies if bleeding is due to anticoagulant therapy. It primarily affects capillary integrity, not coagulation factors.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
In case of an overdose, symptomatic and supportive treatment should be initiated. There is no specific antidote.
Pregnancy & Lactation
Use in pregnancy and lactation only if clearly needed and after consulting a physician. Animal studies have not shown teratogenic effects, but human data are limited.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2 to 3 years from the date of manufacture, when stored as recommended.
Availability
Pharmacies, Hospitals
Approval Status
Approved (DGDA, various countries)
Patent Status
Off-patent
Clinical Trials
Carbazochrome has been in clinical use for many decades. While extensive modern placebo-controlled trials might be limited, its efficacy and safety profile are well-established through clinical experience and older studies.
Lab Monitoring
- Routine laboratory monitoring is generally not required during Carbazochrome therapy.
Doctor Notes
- Ensure correct route of administration (IM/IV).
- Monitor patient for any signs of hypersensitivity during and after administration.
Patient Guidelines
- Inform your doctor about all your medical conditions and medications before starting Carbate injection.
- Report any unusual bleeding or bruising immediately to your doctor.
- Ensure the injection is administered by a qualified healthcare professional.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
Carbate 100 mcg Injection is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Avoid activities that may cause injury or trauma, especially if prone to bleeding.
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