Carbocal
Generic Name
Calcium Carbonate + Vitamin D3
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| carbocal 500 mg tablet | ৳ 2.20 | ৳ 22.00 |
Description
Overview of the medicine
Carbocal is a combined preparation of Calcium Carbonate and Vitamin D3, used to prevent and treat calcium and vitamin D deficiencies. It supports bone health and overall bodily functions.
Uses & Indications
Dosage
Adults
1-2 tablets daily, or as directed by a physician.
Elderly
Same as adult dosage, but caution with renal function.
Renal_impairment
Use with caution. Dosage adjustment may be required based on serum calcium and phosphate levels.
How to Take
Oral administration. Can be taken with or without food, but generally recommended after meals for better absorption and to reduce gastric upset.
Mechanism of Action
Calcium Carbonate provides elemental calcium necessary for bone mineralization, nerve impulse transmission, and muscle contraction. Vitamin D3 (Cholecalciferol) facilitates the absorption of calcium from the gastrointestinal tract and its deposition into bone.
Pharmacokinetics
Onset
Gradual, over weeks to months for bone health benefits.
Excretion
Calcium: Primarily via feces (unabsorbed) and urine. Vitamin D3: Excreted primarily via bile and feces.
Half life
Calcium: Varies. Vitamin D3: 1-2 months for storage form; active metabolite (calcitriol) has a half-life of 3-6 hours.
Absorption
Calcium absorption is primarily in the small intestine and is enhanced by Vitamin D. Vitamin D3 is absorbed from the small intestine, transported to the liver and then kidneys for activation.
Metabolism
Calcium: Not metabolized. Vitamin D3: Hydroxylated in the liver to 25-hydroxyvitamin D3, then in the kidneys to 1,25-dihydroxyvitamin D3 (calcitriol), the active form.
Side Effects
Contraindications
- Hypercalcemia
- Hypervitaminosis D
- Severe renal impairment
- Known hypersensitivity to any component
- Nephrolithiasis
Drug Interactions
Corticosteroids
May reduce calcium absorption.
Thiazide diuretics
May increase risk of hypercalcemia.
Bisphosphonates/Levothyroxine
Reduced absorption if taken concurrently; separate administration by several hours.
Tetracyclines/Fluoroquinolones
Reduced absorption due to chelation; administer at least 2-3 hours apart.
Storage
Store in a cool, dry place, below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, constipation, thirst, polyuria, weakness. Severe cases can lead to renal impairment and cardiac arrhythmias. Management involves discontinuing the product, rehydration, and supportive care.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation within recommended daily allowances, but should be used under medical supervision. Excessive doses may be harmful.
Side Effects
Contraindications
- Hypercalcemia
- Hypervitaminosis D
- Severe renal impairment
- Known hypersensitivity to any component
- Nephrolithiasis
Drug Interactions
Corticosteroids
May reduce calcium absorption.
Thiazide diuretics
May increase risk of hypercalcemia.
Bisphosphonates/Levothyroxine
Reduced absorption if taken concurrently; separate administration by several hours.
Tetracyclines/Fluoroquinolones
Reduced absorption due to chelation; administer at least 2-3 hours apart.
Storage
Store in a cool, dry place, below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, constipation, thirst, polyuria, weakness. Severe cases can lead to renal impairment and cardiac arrhythmias. Management involves discontinuing the product, rehydration, and supportive care.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation within recommended daily allowances, but should be used under medical supervision. Excessive doses may be harmful.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from the date of manufacture.
Availability
Available in all pharmacies and drugstores
Approval Status
Approved by DGDA
Patent Status
Off-patent
Clinical Trials
Extensive clinical trials have established the efficacy and safety of calcium and vitamin D supplementation in preventing and treating bone health issues.
Lab Monitoring
- Serum calcium levels
- Serum vitamin D levels (25-OH D)
- Renal function tests (creatinine, eGFR)
Doctor Notes
- Consider baseline calcium and vitamin D levels before initiating therapy.
- Educate patients on dietary calcium intake and moderate sun exposure.
- Monitor renal function in elderly or patients with pre-existing kidney conditions.
Patient Guidelines
- Take exactly as prescribed or directed.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
- Report any unusual or severe side effects to your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
No known adverse effects on the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and vitamin D.
- Regular weight-bearing exercise helps bone health.
- Moderate sun exposure can help with natural vitamin D synthesis.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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