Cartil
Generic Name
Glucosamine Sulfate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cartil 250 mg tablet | ৳ 8.03 | ৳ 80.27 |
Description
Overview of the medicine
Cartil 250 mg tablet contains Glucosamine Sulfate, a naturally occurring amino sugar crucial for healthy cartilage. It is used as a dietary supplement to support joint health, reduce pain and inflammation associated with osteoarthritis, and promote cartilage regeneration.
Uses & Indications
Dosage
Adults
Typically 1000-1500 mg Glucosamine Sulfate daily, divided into 1-3 doses. For 250 mg tablets, this would be 4-6 tablets daily.
Elderly
Same as adult dosage; no specific adjustment generally needed.
Renal_impairment
No specific dosage adjustment guidelines; use with caution. Consult a physician.
How to Take
Oral administration. Can be taken with or without food. Taking with food may help reduce potential gastrointestinal discomfort.
Mechanism of Action
Glucosamine is a precursor for glycosaminoglycans (GAGs) and proteoglycans, which are major components of cartilage. It helps in the synthesis of cartilage and synovial fluid, potentially slowing down cartilage degradation and improving joint function by maintaining the structural integrity of joint tissues.
Pharmacokinetics
Onset
Therapeutic effects may take several weeks to manifest (e.g., 2-4 weeks) with consistent use.
Excretion
Primarily excreted via urine (approximately 10%), with some fecal excretion.
Half life
Plasma half-life is approximately 15-18 hours.
Absorption
Oral bioavailability is estimated around 25-26%. Rapidly absorbed from the gastrointestinal tract.
Metabolism
Metabolized primarily in the liver, partially through first-pass metabolism.
Side Effects
Contraindications
- Hypersensitivity to glucosamine or any components of the formulation
- Shellfish allergy (if the product is derived from shellfish)
Drug Interactions
Antidiabetic medications
Glucosamine may affect blood glucose levels; diabetic patients should monitor their blood sugar closely.
Warfarin and other anticoagulants
May increase the International Normalized Ratio (INR) and bleeding risk. Close monitoring is advised.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Glucosamine is generally well-tolerated even at higher doses. Symptoms of overdose may include nausea, vomiting, diarrhea, or headache. Management is supportive and symptomatic.
Pregnancy & Lactation
Use with caution during pregnancy and lactation. Limited data available on safety. Consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 to 36 months from the date of manufacture when stored under recommended conditions.
Availability
Pharmacies, drug stores, health stores
Approval Status
Regulated as a dietary supplement/OTC drug
Patent Status
Generic / Off-patent
Clinical Trials
Numerous clinical trials have investigated the efficacy of glucosamine sulfate in osteoarthritis, with varied results. While some studies show benefit in reducing pain and improving function, particularly in mild to moderate cases, others have shown minimal effect.
Lab Monitoring
- Blood glucose levels (for diabetic patients)
- INR (International Normalized Ratio) for patients on warfarin or other anticoagulants
Doctor Notes
- Educate patients on the delayed onset of action and manage expectations regarding symptomatic relief.
- Advise diabetic patients to monitor blood glucose levels closely.
- Consider potential interactions with anticoagulants, and monitor INR if co-administered.
Patient Guidelines
- Take the medicine regularly as prescribed for best results.
- Do not exceed the recommended daily dose.
- Inform your doctor if symptoms worsen or if you experience any unusual side effects.
- It may take several weeks to notice the full therapeutic effects.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.
Driving Precautions
Generally safe. Glucosamine Sulfate is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a healthy body weight to reduce stress on joints.
- Engage in regular low-impact exercises like swimming or walking.
- Follow a balanced diet rich in fruits, vegetables, and whole grains.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.