Take orally, preferably with or after food to minimize gastrointestinal upset. Swallow the tablet whole with a sufficient amount of liquid.

Aceclofenac primarily acts by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins, inflammatory mediators. It demonstrates higher selectivity for COX-2 than COX-1, which may contribute to a better gastrointestinal tolerability profile compared to some other NSAIDs.

• •Hypersensitivity to aceclofenac or any excipients
• •Patients with a history of asthma, urticaria, or acute rhinitis precipitated by aspirin or other NSAIDs
• •Active or recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding)
• •Severe heart failure, severe hepatic insufficiency, or severe renal insufficiency
• •Third trimester of pregnancy
• •History of gastrointestinal bleeding or perforation related to previous NSAID therapy

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.

Symptoms of overdose include headache, nausea, vomiting, epigastric pain, gastrointestinal bleeding, rarely diarrhoea, disorientation, excitation, coma, drowsiness, dizziness, tinnitus and fainting. Acute renal failure and liver damage are possible. Management involves symptomatic and supportive treatment. Gastric lavage or activated charcoal may be considered.

Pregnancy Category C (first two trimesters), D (third trimester). Should be avoided during pregnancy, especially in the third trimester due to potential adverse effects on the fetus (e.g., premature closure of ductus arteriosus). Use with caution during lactation; consult a doctor.