Ceevit
Generic Name
Ascorbic Acid (Vitamin C)
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ceevit 100 mg syrup | ৳ 40.00 | N/A |
| ceevit 250 mg chewable tablet | ৳ 1.90 | ৳ 19.00 |
Description
Overview of the medicine
Ceevit is a brand of Ascorbic Acid (Vitamin C), an essential water-soluble vitamin known for its antioxidant properties and crucial role in immune function, collagen formation, and wound healing.
Uses & Indications
Dosage
Adults
For deficiency: 250 mg to 1000 mg daily. For scurvy: 250 mg to 1 g, 1-3 times daily for at least 2 weeks. For general antioxidant support: 250-500 mg daily.
Elderly
Dosage generally similar to adults, but caution should be exercised with high doses in patients with pre-existing renal conditions.
Renal_impairment
Use with caution in patients with severe renal impairment due to increased risk of oxalate nephropathy, especially with high doses. Lower doses may be advisable.
How to Take
Take orally, with or without food. Chewable tablets should be thoroughly chewed before swallowing.
Mechanism of Action
Ascorbic acid acts as an antioxidant, protecting cells from damage caused by free radicals. It is a vital cofactor for several enzyme systems involved in collagen synthesis, carnitine synthesis, and neurotransmitter biosynthesis. It also enhances iron absorption and supports immune cell function.
Pharmacokinetics
Onset
Clinical effects for deficiency may take days to weeks to manifest.
Excretion
Excreted primarily in the urine as unchanged ascorbic acid and its metabolites. Renal excretion increases with higher doses.
Half life
Approximately 10-20 days in the body pool at normal saturation, but shorter in deficient states.
Absorption
Readily absorbed from the gastrointestinal tract, primarily in the small intestine, through an active transport process.
Metabolism
Partially metabolized in the liver to inactive metabolites like dehydroascorbic acid, 2,3-diketogulonic acid, and oxalic acid.
Side Effects
Contraindications
- Hypersensitivity to ascorbic acid or any component of the formulation
- Individuals with hyperoxaluria or a history of oxalate kidney stones should avoid high doses
Drug Interactions
Warfarin
High doses of ascorbic acid may interfere with the anticoagulant effect of warfarin, requiring closer monitoring of INR.
Desferrioxamine
Concurrent use with desferrioxamine in iron-overloaded patients may increase iron toxicity, particularly cardiotoxicity.
Oral Contraceptives
Oral contraceptives may lower plasma vitamin C levels.
Aluminum-containing antacids
Ascorbic acid can increase the absorption of aluminum from antacids, which can be problematic in patients with renal impairment.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare due to its water-soluble nature. Symptoms may include gastrointestinal upset (nausea, vomiting, diarrhea), headache, and flushing. In severe cases, high doses can lead to oxalate nephropathy and renal stone formation. Treatment is supportive and symptomatic.
Pregnancy & Lactation
Considered safe when taken in recommended daily allowances during pregnancy and lactation. High doses should be avoided unless prescribed by a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2 to 3 years from the date of manufacture.
Availability
Available in all pharmacies and drug stores
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensively studied and widely used; specific clinical trials for the Ceevit brand are not typically published, but for Ascorbic Acid, numerous studies exist on its efficacy in various conditions.
Doctor Notes
- Advise patients on the importance of a balanced diet rich in Vitamin C.
- Caution patients with a history of kidney stones about high doses of Vitamin C.
- Explain that while Vitamin C is an antioxidant, it does not cure all ailments and is best used as a supplement for deficiency or support.
Patient Guidelines
- Take exactly as directed by your doctor or as indicated on the label.
- Chew chewable tablets thoroughly before swallowing.
- Do not exceed the recommended dose without consulting a healthcare professional.
- Store in a cool, dry place away from direct sunlight and moisture.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Ceevit is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits and vegetables, which are natural sources of Vitamin C.
- Stay hydrated by drinking adequate water throughout the day.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.