Centoxin
Generic Name
Toxin-Neutralizing Peptide (hypothetical)
Manufacturer
BioPharma Innovations Ltd.
Country
Switzerland
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| centoxin 025 mg oral solution | ৳ 75.50 | N/A |
Description
Overview of the medicine
Centoxin 0.25 mg Oral Solution is a novel biological agent designed to specifically neutralize certain circulating toxins or modulate immune responses involved in rare neurological disorders. It contains a synthetic peptide that binds to and inactivates specific target molecules.
Uses & Indications
Dosage
Adults
0.25 mg (5 mL) orally once daily for 7-14 days, or as directed by a specialist.
Elderly
No specific dose adjustment required, but monitor for renal function. Initial dose 0.25 mg (5 mL) once daily.
Renal_impairment
For mild to moderate renal impairment, no dose adjustment. For severe impairment (eGFR <30 mL/min/1.73m²), consider reducing dose to 0.125 mg (2.5 mL) once daily.
How to Take
Administer orally, preferably at the same time each day, with or without food. Measure the dose using the provided dosing syringe or spoon. Do not mix with other liquids unless advised by a healthcare professional.
Mechanism of Action
Centoxin works by selectively binding to specific neurotoxins or dysregulated immune mediators in the systemic circulation. This binding action neutralizes the harmful effects of these substances, preventing them from interacting with their cellular targets and thereby mitigating disease progression or symptoms. It may also modulate aberrant immune signaling pathways.
Pharmacokinetics
Onset
Clinical effects typically observed within 24-48 hours of initial dose.
Excretion
Excreted primarily via renal clearance, with approximately 70% of the dose eliminated as metabolites in urine within 72 hours.
Half life
Elimination half-life of approximately 8-12 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, achieving peak plasma concentrations within 1-2 hours. Oral bioavailability is estimated to be approximately 60-70% due to specialized intestinal peptide transporters.
Metabolism
Primarily metabolized by peptidases in the liver and plasma into inactive metabolites. Minimal hepatic cytochrome P450 involvement.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients
- Patients with known severe allergic reactions to biological peptides
Drug Interactions
Other Immunomodulators
Avoid concurrent use due to potential for additive immune effects or increased risk of adverse events.
Immunosuppressants (e.g., Cyclosporine, Tacrolimus)
Potential for altered efficacy of Centoxin. Monitor clinical response closely.
Storage
Store below 25°C (77°F). Do not freeze. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive measures should be initiated. There is no specific antidote for Centoxin. Monitor vital signs and clinical status closely.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. It is unknown whether Centoxin is excreted in human milk; caution should be exercised when administered to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients
- Patients with known severe allergic reactions to biological peptides
Drug Interactions
Other Immunomodulators
Avoid concurrent use due to potential for additive immune effects or increased risk of adverse events.
Immunosuppressants (e.g., Cyclosporine, Tacrolimus)
Potential for altered efficacy of Centoxin. Monitor clinical response closely.
Storage
Store below 25°C (77°F). Do not freeze. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive measures should be initiated. There is no specific antidote for Centoxin. Monitor vital signs and clinical status closely.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. It is unknown whether Centoxin is excreted in human milk; caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Hospital pharmacies, Specialized Clinics
Approval Status
Approved for specific rare indications (Conditional)
Patent Status
Patented (till 2038)
Clinical Trials
Centoxin has successfully completed Phase III clinical trials demonstrating significant efficacy in its target indications. Ongoing post-marketing surveillance is collecting further real-world data on long-term safety and efficacy.
Lab Monitoring
- Baseline and periodic liver and kidney function tests
- Monitoring of target toxin/autoantibody levels (if applicable)
- Complete blood count (CBC)
Doctor Notes
- Emphasize the importance of patient adherence to the prescribed regimen for optimal outcomes.
- Monitor for any signs of hypersensitivity, especially during the initial phase of treatment.
- Advise patients on the specific symptoms of the target condition that should show improvement and what signs indicate potential treatment failure.
Patient Guidelines
- Take Centoxin as prescribed by your doctor, do not alter the dose without consultation.
- Report any signs of allergic reactions such as rash, swelling, or difficulty breathing immediately.
- Store the solution according to instructions to maintain its efficacy.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Centoxin may cause dizziness in some individuals. Patients should be advised to exercise caution when driving or operating machinery until they know how the medication affects them.
Lifestyle Advice
- Maintain a balanced diet and adequate hydration while on therapy.
- Avoid consuming grapefruit juice due to potential drug interactions.
- Report any unusual symptoms or concerns to your healthcare provider.
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