CFB
Generic Name
Ceftibuten
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cfb 100 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Ceftibuten is a broad-spectrum, third-generation cephalosporin antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
200 mg (2 tablets) twice daily or 400 mg (4 tablets) once daily, depending on infection type and severity, typically for 5-10 days.
Elderly
Same as adult dose, but monitor renal function due to potential age-related decline.
Renal_impairment
Dosage adjustment required in severe renal impairment; consult physician based on creatinine clearance.
How to Take
Oral administration, can be taken with or without food. For optimal absorption, some sources recommend taking it without food.
Mechanism of Action
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death.
Pharmacokinetics
Onset
1-2 hours
Excretion
Primarily excreted unchanged in the urine.
Half life
2-4 hours
Absorption
Rapidly absorbed from the gastrointestinal tract, unaffected by food.
Metabolism
Minimal hepatic metabolism.
Side Effects
Contraindications
- Hypersensitivity to ceftibuten or any other cephalosporin antibiotics.
- History of severe allergic reaction to penicillin (due to potential cross-reactivity).
Drug Interactions
Antacids
Certain antacids may decrease the absorption of ceftibuten; separate administration times.
Warfarin
May enhance the anticoagulant effect of warfarin, requiring close monitoring of INR.
Probenecid
Increases ceftibuten plasma levels by reducing renal excretion.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment is recommended. Hemodialysis may be useful in reducing serum ceftibuten concentrations.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed after consulting a physician. Ceftibuten is excreted in breast milk in small amounts; use with caution in lactating mothers.
Side Effects
Contraindications
- Hypersensitivity to ceftibuten or any other cephalosporin antibiotics.
- History of severe allergic reaction to penicillin (due to potential cross-reactivity).
Drug Interactions
Antacids
Certain antacids may decrease the absorption of ceftibuten; separate administration times.
Warfarin
May enhance the anticoagulant effect of warfarin, requiring close monitoring of INR.
Probenecid
Increases ceftibuten plasma levels by reducing renal excretion.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment is recommended. Hemodialysis may be useful in reducing serum ceftibuten concentrations.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed after consulting a physician. Ceftibuten is excreted in breast milk in small amounts; use with caution in lactating mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Expired
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have been conducted demonstrating the efficacy and safety of Ceftibuten in treating various susceptible bacterial infections.
Lab Monitoring
- Renal function tests (especially in elderly or patients with pre-existing renal impairment)
- Liver function tests (for prolonged therapy)
- INR (if co-administered with warfarin)
Doctor Notes
- Emphasize the importance of completing the full antibiotic course to prevent resistance.
- Advise patients to report any signs of allergic reactions, particularly in those with a history of penicillin allergy.
- Exercise caution and adjust dosage in patients with severe renal impairment.
Patient Guidelines
- Complete the full course of treatment as prescribed, even if you feel better.
- Do not skip doses or stop treatment early, as this can lead to antibiotic resistance.
- Inform your doctor or pharmacist about all other medications you are taking.
- Report any severe or persistent side effects to your doctor immediately.
Missed Dose Advice
Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness in some individuals. Exercise caution when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Stay well-hydrated during treatment.
- Avoid alcohol consumption while taking antibiotics.
- Maintain good hygiene to prevent spread of infection.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.