Chemocain
Generic Name
Chemocain-2-Injection
Manufacturer
PharmaCorp
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| chemocain 2 injection | ৳ 28.65 | N/A |
Description
Overview of the medicine
Chemocain-2-injection is a local anesthetic used to numb specific areas of the body before minor surgical procedures or to relieve pain.
Uses & Indications
Dosage
Adults
Varies based on procedure, site, and patient response. Typically 1-5 mL (2-10 mg) of 2 mg/mL solution.
Elderly
Reduced doses may be required due to decreased hepatic function and sensitivity.
Renal_impairment
No specific dosage adjustment for mild to moderate impairment; monitor for severe cases.
How to Take
Administered by healthcare professional via injection into the target area.
Mechanism of Action
Blocks nerve impulse conduction by inhibiting sodium ion influx through voltage-gated sodium channels in neuronal membranes.
Pharmacokinetics
Onset
2-5 minutes (infiltration)
Excretion
Renal excretion of metabolites and unchanged drug.
Half life
Approximately 1.5-2 hours
Absorption
Rapidly absorbed from the injection site, especially in highly vascularized areas. Absorption rate depends on vascularity and dose.
Metabolism
Primarily hepatic metabolism by amidase enzymes.
Side Effects
Contraindications
- Hypersensitivity to amide-type local anesthetics
- Severe atrioventricular block
- Intravenous regional anesthesia in patients with impaired cardiovascular function
Drug Interactions
Beta-blockers
Reduced hepatic blood flow, potentially leading to increased Chemocain levels.
Antiarrhythmics (e.g., mexiletine)
Increased risk of cardiac depression.
Storage
Store below 25°C, protect from light. Do not freeze.
Overdose
Symptoms include CNS excitation (seizures), followed by CNS depression (respiratory arrest), and cardiovascular depression (hypotension, bradycardia). Management involves supportive care, maintaining airway, oxygenation, and treating seizures/cardiac issues.
Pregnancy & Lactation
Use with caution; consult physician. Category B for pregnancy. Excreted in breast milk in small amounts, generally considered safe.
Side Effects
Contraindications
- Hypersensitivity to amide-type local anesthetics
- Severe atrioventricular block
- Intravenous regional anesthesia in patients with impaired cardiovascular function
Drug Interactions
Beta-blockers
Reduced hepatic blood flow, potentially leading to increased Chemocain levels.
Antiarrhythmics (e.g., mexiletine)
Increased risk of cardiac depression.
Storage
Store below 25°C, protect from light. Do not freeze.
Overdose
Symptoms include CNS excitation (seizures), followed by CNS depression (respiratory arrest), and cardiovascular depression (hypotension, bradycardia). Management involves supportive care, maintaining airway, oxygenation, and treating seizures/cardiac issues.
Pregnancy & Lactation
Use with caution; consult physician. Category B for pregnancy. Excreted in breast milk in small amounts, generally considered safe.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials support its efficacy and safety as a local anesthetic.
Lab Monitoring
- Monitor vital signs during and after administration
- Monitor for signs of systemic toxicity
Doctor Notes
- Ensure aspiration before injection to avoid intravascular administration.
- Monitor for systemic toxicity, especially in pediatric or elderly patients.
Patient Guidelines
- Inform your doctor about all medical conditions and medications.
- Report any unusual sensations or discomfort during or after injection.
- Avoid touching or applying pressure to the numb area until sensation returns.
Missed Dose Advice
Not applicable as it is administered by a healthcare professional.
Driving Precautions
Avoid driving or operating machinery until the effects of anesthesia have completely worn off and normal sensation/coordination returns.
Lifestyle Advice
- Follow post-procedure instructions given by your healthcare provider.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.