chrocee
Generic Name
Chromium Picolinate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| chrocee 200 mg capsule | ৳ 35.00 | ৳ 140.00 |
Description
Overview of the medicine
Chromium Picolinate is a trace mineral supplement primarily used to support glucose metabolism and enhance insulin sensitivity. It is also explored for its potential role in weight management.
Uses & Indications
Dosage
Adults
Usually 200 mg (Chromium Picolinate) once daily, or as directed by a healthcare professional. Doses may vary based on specific needs.
Elderly
No specific dose adjustment required for elderly, but caution is advised in those with pre-existing renal impairment.
Renal_impairment
Use with caution. Dose reduction or monitoring may be necessary due to renal excretion. Consult a physician.
How to Take
Chrocee-200 mg capsule should be taken orally, with or without food. It can be taken at any time of the day.
Mechanism of Action
Chromium is thought to potentiate the action of insulin by affecting its receptor affinity or by influencing post-receptor signaling pathways, thereby improving glucose uptake and metabolism. Chromium picolinate is a highly bioavailable form.
Pharmacokinetics
Onset
Effects on blood glucose or lipid parameters are gradual and may take several weeks to manifest.
Excretion
Primarily excreted unchanged via the kidneys in urine, with minor fecal excretion.
Half life
The plasma half-life of chromium is estimated to be between 2-10 hours, but it accumulates in tissues.
Absorption
Absorption of chromium picolinate is variable but generally low (0.4-2.5% of the dose), higher than inorganic chromium forms.
Metabolism
Chromium itself is not significantly metabolized; it functions as an active ion.
Side Effects
Contraindications
- Hypersensitivity to chromium or any component of the formulation.
- Severe pre-existing kidney or liver disease (use with extreme caution or avoid).
Drug Interactions
Levothyroxine (Thyroid Hormones)
Chromium may affect the absorption of thyroid hormones; administer at least 3-4 hours apart.
Antacids, H2 Blockers, Proton Pump Inhibitors
These medications may reduce the absorption of chromium; separate administration times.
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Some NSAIDs may potentially increase chromium levels; monitor if co-administered.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose of chromium picolinate is rare but may lead to renal damage, liver dysfunction, or blood disorders. Treatment is primarily supportive and symptomatic.
Pregnancy & Lactation
Chromium is an essential nutrient. While generally considered safe at recommended dietary intake levels, high supplemental doses during pregnancy and lactation should only be taken under medical supervision.
Side Effects
Contraindications
- Hypersensitivity to chromium or any component of the formulation.
- Severe pre-existing kidney or liver disease (use with extreme caution or avoid).
Drug Interactions
Levothyroxine (Thyroid Hormones)
Chromium may affect the absorption of thyroid hormones; administer at least 3-4 hours apart.
Antacids, H2 Blockers, Proton Pump Inhibitors
These medications may reduce the absorption of chromium; separate administration times.
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Some NSAIDs may potentially increase chromium levels; monitor if co-administered.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose of chromium picolinate is rare but may lead to renal damage, liver dysfunction, or blood disorders. Treatment is primarily supportive and symptomatic.
Pregnancy & Lactation
Chromium is an essential nutrient. While generally considered safe at recommended dietary intake levels, high supplemental doses during pregnancy and lactation should only be taken under medical supervision.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 to 36 months from the date of manufacture, refer to the product packaging for exact date.
Availability
Pharmacies, supermarkets, health stores
Approval Status
Generally Recognized As Safe (GRAS) by FDA for some uses, regulated as a dietary supplement.
Patent Status
Off-patent
Clinical Trials
Numerous clinical trials have investigated Chromium Picolinate's effects on glucose metabolism, insulin sensitivity, and lipid profiles in individuals with type 2 diabetes and insulin resistance. Research on its efficacy for weight loss is ongoing.
Lab Monitoring
- Blood glucose levels (for diabetic patients)
- Glycosylated Hemoglobin (HbA1c) in diabetics
- Kidney function tests (e.g., creatinine, BUN) in patients with renal impairment.
Doctor Notes
- Advise patients that Chromium Picolinate is a supplement, not a cure for diabetes or obesity.
- Monitor blood glucose levels regularly in diabetic patients.
- Caution advised in patients with pre-existing renal or liver conditions.
- Counsel patients on healthy diet and lifestyle alongside supplementation.
Patient Guidelines
- Take Chrocee-200 mg capsule as directed by your healthcare provider.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications and supplements you are taking.
- Report any unusual or severe side effects to your doctor immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Chrocee-200 mg capsule is generally not expected to affect the ability to drive or operate machinery. However, if you experience side effects like dizziness or drowsiness, avoid such activities.
Lifestyle Advice
- Maintain a balanced diet rich in whole foods.
- Engage in regular physical activity.
- Chromium supplements are not a substitute for a healthy lifestyle or prescribed medications for diabetes.
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International brand names for this medicine. Click a brand to search for detailed information.