Take the tablet orally with a glass of water, preferably on an empty stomach or at least 2 hours after a meal. Avoid taking with dairy products or antacids containing magnesium/aluminum/calcium.

Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Dexamethasone exerts its anti-inflammatory and immunosuppressive effects by binding to cytoplasmic glucocorticoid receptors, modifying gene expression to reduce the synthesis of inflammatory mediators and inhibit immune cell function.

• •Hypersensitivity to ciprofloxacin, other fluoroquinolones, dexamethasone, or any component of the formulation.
• •History of tendinitis or tendon rupture associated with quinolone use.
• •Concurrent use with Tizanidine.
• •Systemic fungal infections (for dexamethasone).

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

In case of Ciprofloxacin overdose, symptoms may include nausea, vomiting, diarrhea, headache, dizziness, tremors, hallucinations, and seizures. Dexamethasone acute overdose is unlikely to cause life-threatening effects but chronic overdose can lead to Cushingoid features, hyperglycemia, and fluid retention. Treatment is symptomatic and supportive, including gastric lavage and adequate hydration.

Ciprofloxacin is generally not recommended during pregnancy due to potential effects on fetal cartilage development. Dexamethasone may be used if benefits outweigh risks, but is also generally avoided. Both Ciprofloxacin and Dexamethasone are excreted in breast milk. Use during pregnancy and lactation should only be considered if clearly necessary and with careful risk-benefit assessment by a physician.