Cinagen
Generic Name
Ciprofloxacin Ophthalmic Solution 0.5%
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cinagen 05 eye drop | ৳ 140.00 | N/A |
Description
Overview of the medicine
Ciprofloxacin ophthalmic solution is a fluoroquinolone antibiotic used to treat bacterial infections of the eye.
Uses & Indications
Dosage
Adults
For bacterial conjunctivitis: 1-2 drops into the affected eye(s) every 2 hours while awake for 2 days, then 1-2 drops every 4 hours while awake for the next 5 days. For corneal ulcers: Initially, 2 drops into the affected eye(s) every 15 minutes for 6 hours, then 2 drops every 30 minutes for the remainder of the first day. On the second day, 2 drops every hour. From day 3-14, 2 drops every 4 hours.
Elderly
No specific dosage adjustment required.
Renal_impairment
Not applicable for ophthalmic use due to minimal systemic absorption.
How to Take
Instill drops into the conjunctival sac. Avoid touching the dropper tip to the eye or any other surface to prevent contamination.
Mechanism of Action
Inhibits bacterial DNA gyrase and topoisomerase IV, essential for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death.
Pharmacokinetics
Onset
Rapid, typically within hours for symptomatic relief.
Excretion
Primarily renal for systemically absorbed drug. Ocular elimination is local tear turnover.
Half life
Systemic half-life is 3-5 hours, but ocular kinetics are different and systemic relevance is minimal.
Absorption
Minimal systemic absorption after ocular administration. Local absorption in ocular tissues.
Metabolism
Minimal ocular metabolism. Systemic metabolism primarily hepatic.
Side Effects
Contraindications
- Hypersensitivity to Ciprofloxacin or any other quinolone antibiotics
- Viral or fungal eye infections
Drug Interactions
Other ophthalmic preparations
Minimal systemic absorption, so drug interactions are rare. However, avoid co-administration with other ophthalmic preparations without consulting a doctor.
Storage
Store at room temperature (15-30°C). Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Not expected with ophthalmic use due to minimal absorption. If accidental ingestion, induce vomiting or gastric lavage if appropriate.
Pregnancy & Lactation
Use only if clearly needed. Consult a doctor. Pregnancy Category C.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials supported the efficacy and safety of ciprofloxacin ophthalmic solution for bacterial eye infections.
Lab Monitoring
- Not typically required for ophthalmic use.
Doctor Notes
- Educate patients on proper instillation technique to avoid contamination.
- Advise patients to report any signs of hypersensitivity or severe eye irritation immediately.
- Ensure patients complete the full course of treatment even if symptoms improve early.
Patient Guidelines
- Do not wear contact lenses during treatment
- Wash hands before and after applying drops
- Complete the full course of treatment even if symptoms improve
Missed Dose Advice
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision; caution when driving or operating machinery immediately after administration.
Lifestyle Advice
- Avoid touching eyes unnecessarily
- Maintain good eye hygiene
- Avoid eye makeup during active infection
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.